Sort   by:  
 Page size 
TranscriptomicsFibroblast-like synoviocytes derived from patients with rheumatoid arthritis
Fibroblast-like synoviocytes (FLS) were cultured from synovial tissues from 19 RA patients. RNA was isolated using the Fast Track 2.0 kit (Invitrogen, Carlsbad, California)from the FLS cultures. Fluorescent cDNA probes were prepared from 1 ug experimental mRNA by oligo dT-primed polymerization using...
ORGANISM(S): Homo sapiens 
2006-01-18 | E-GEOD-4061 | biostudies-arrayexpress
ProteomicsThe role of GATD3A in regulating Fibroblast-like synoviocytes functions
The role of GATD3A (glutamine amidotransferase-like class 1 domain-containing 3A) in regulating functions of fibroblast-like synoviocytes was assessed by lentivirus infection and label-free proteomics assay.
ORGANISM(S): Homo Sapiens 
2024-08-30 | PXD055034 |
TranscriptomicsRNA expression profiles in fibroblast-like synoviocytes from rheumatoid arthritis patients and trauma patients
LncRNA and mRNA microarrays were performed to identify differentially expressed lncRNAs and mRNAs in fibroblast-like synoviocytes from rheumatoid arthritis patients compared with fibroblast-like synoviocytes from trauma patients. Fibroblast-like synoviocytes were isolated from synovial tissues. LncR...
ORGANISM(S): Homo sapiens 
2016-06-10 | E-GEOD-83147 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of normal and Mucopolysaccharidosis type VI rat fibroblast-like synoviocytes
Gene expression in 9 month-old Mucopolysaccharidosis type VI rat fibroblast-like synoviocytes (FLS) were compared to age-matched normal rat FLS
ORGANISM(S): Rattus norvegicus 
2007-10-24 | E-TABM-306 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression profiles of synoviocytes and macrophages in patients with rheumatoid arthritis and osteoarthritis
Rheumatoid synoviocytes, which consist of fibroblast-like synoviocytes (FLS) and synovial macrophages (SM), are crucial for the progression of rheumatoid arthritis (RA). Particularly, FLS of RA patients (RA-FLS) exhibit invasive characteristics reminiscent of cancer cells, destroying cartilage and b...
ORGANISM(S): Homo sapiens 
2014-01-09 | E-GEOD-49604 | biostudies-arrayexpress
TranscriptomicsExpression data from fibroblast-like synoviocytes (FLS) transfected with mimic-miR-23b or mimic-NC
We found microRNA miR-23b was down-regulated in local inflammatory tissues of autoimmune disease such as RA, SLE and related mouse models such as CIA, lpr, EAE. Re-expression of miR-23b significantly inhibits autoimmune pathogenesis of CIA, Lpr and EAE. To identify potential targets of miR-23b, we u...
ORGANISM(S): Homo sapiens 
2012-12-19 | E-GEOD-37427 | biostudies-arrayexpress
ProteomicsHuman fibroblast-like synoviocytes (FLSs) -derived secretome
Invasive pannus, mainly composed of fibroblast-like synoviocytes (FLSs), is a hallmark of rheumatoid arthritis (RA) pathology. Secreted proteins from RA-FLS play key roles in RA invasive pannus. However, RA-FLS-derived secretome associated with invasive pannus has not been systematically investigate...
ORGANISM(S): Homo sapiens (Human) 
2023-06-30 | PXD041077 | Pride
Rheumatoid arthritis Secretome Fibroblast-like synoviocytes 
Proteomicscapsaicin ameliorates rheumatoid arthritis via ROS-mediated apoptosis in fibroblast-like synoviocytes
In this project we discovered that CAP not only reduces joint swelling in arthritic model mice but also exhibits anti-inflammatory and antiproliferative effects on fibroblast-like synoviocytes (FLS). By synthesizing alkyne-tagged CAP probes and employing activity-based protein profiling (ABPP), we i...
ORGANISM(S): Homo Sapiens 
2024-11-07 | PXD057639 |
GenomicsTranscriptome profile of fibroblast-like synoviocytes with FTO knockdown
Transcriptome profile of fibroblast-like synoviocytes with FTO knockdown
PRJNA1007586 | ENA
ProteomicsInhibition Peroxiredoxin-2 by capsaicin ameliorates rheumatoid arthritis via ROS-mediated apoptosis in fibroblast-like synoviocytes
In this project we discovered that CAP not only reduces joint swelling in arthritic model mice but also exhibits anti-inflammatory and antiproliferative effects on fibroblast-like synoviocytes (FLS). By synthesizing alkyne-tagged CAP probes and employing activity-based protein profiling (ABPP), we i...
ORGANISM(S): Homo Sapiens 
2024-11-12 | PXD057819 |
Sort   by:  
 Page size