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UnknownLoss of FilaminC (FLNc) results in severe defects in myogenesis and myotube structure.
Not available
S-EPMC1592847 | biostudies-literature
ProteomicsFilaminC pull-down experiment from myotube lysates
This project was designed to identify a difference in the binding affinity of FILIP1 to different FLNc variants. To this end FLNc domain 1-3 and FLNc d18-21 were used as bait for a pull-down analysis.
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2020-05-25 | PXD017670 | Pride
Pull-down Myotube lysate Flnc 
UnknownFilamin C promotes lymphatic invasion and lymphatic metastasis and increases cell motility by regulating Rho GTPase in esophageal squamous cell carcinoma.
Not available
S-EPMC5351637 | biostudies-literature
UnknownFilamin C regulates skeletal muscle atrophy by stabilizing dishevelled-2 to inhibit autophagy and mitophagy.
Not available
S-EPMC8683659 | biostudies-literature
ProteomicsHomozygous expression of the myofibrillar myopathy-associated p.W2710X filamin C variant reveals major pathomechanisms of sarcomeric lesion formation
Filamin C is mainly expressed in striated muscle cells where it localizes to Z-discs, myotendinous junctions and intercalated discs. Recent studies have revealed numerous mutations in the FLNC gene causing familiar and sporadic myopathies and cardiomyopathies with marked clinical variability. The mo...
ORGANISM(S): Mus musculus (Mouse) 
2020-09-09 | PXD020097 | Pride
Lasermicrodissection Myofibrillar myopathies Filaminc Neuromuscular disorders Proteomics 
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