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TranscriptomicsThe genomic landscape of cohesin-associated chromatin interactions
Cohesin is implicated in establishing tissue-specific DNA loops that target enhancers to promoters, and also localizes to sites bound by the insulator protein CTCF, which blocks enhancer-promoter communication. However, cohesin-associated interactions have not been characterized on a genome-wide sca...
ORGANISM(S): Mus musculus 
2013-05-22 | E-GEOD-42237 | biostudies-arrayexpress
TranscriptomicsRNA-seq of coding RNA of Actinoplanes sp. SE50/110 to analyze gene function of alternative sigma factor gene ACSP50_0507
Cultivation in maltose minimal media and sampling at different time point (t2 = 96h; t3=118h; t4 = 142h; t5 = 166h) of Actinoplanes sp. SE50/110 empty vector control and Actinoplanes sp. SE50/110 ACSP50_0507 overxepression mutant. RNAseq material and methods
ORGANISM(S): Actinoplanes sp. SE50/110 
2024-07-22 | E-MTAB-13644 | biostudies-arrayexpress
TranscriptomicsGroup B meningococcus (M1239) - Wild type and M2-D strains grown at mid log in GC broth and stressed with 100uM dipyridil
Analysis of global transcription profile of wild type M1239 and M2-D strains grown at mid log in GC broth until mid log phase and stressed with 100uM dipyridyl
ORGANISM(S): Neisseria meningitidis 
2011-09-27 | E-MTAB-687 | biostudies-arrayexpress
TranscriptomicsNeuropeptides:developmental signals in placode progenitor formation
Few families of signaling factors have been implicated in the control of development. Here we identify the neuropeptides nociceptin and somatostatin, a neurotransmitter and neuroendocrine hormone, as a class of developmental signals in chick and zebrafish. We show that signals from the anterior mese...
ORGANISM(S): Gallus gallus 
2014-04-25 | E-GEOD-48116 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae histone H4 wild type and K91A mutant strain cultures
Yeast strain containing either a histone H4 wild type or K91A allele was grown in YPD to mid-log phase and harvested. Three replicates of each allele were performed
ORGANISM(S): Saccharomyces cerevisiae 
2007-07-07 | E-GEOD-2349 | biostudies-arrayexpress
TranscriptomicsComorbidity-Specific Molecular Programs of Early Diastolic Dysfunction Identify Glucocorticoid Receptor Activation as a Causal Driver in Obesity
Early diastolic dysfunction precedes the development of HFpEF, but the molecular events that initiate this process remain poorly defined. HFpEF arises in the setting of systemic comorbidities such as obesity, hypertension, hyperglycemia, and sleep apnea, which often coexist and make it difficult to ...
ORGANISM(S): Mus musculus 
2026-07-03 | E-MTAB-16848 | biostudies-arrayexpress
TranscriptomicsStranded Total RNA-seq of liver biopsy collected from Holstein Friesian cows that were defined from cluster analysis as being metabolically "balanced", "imbalanced" or "other
Homeorhetic mechanisms assist dairy cows to transition from pregnancy to lactation. In some cows this is less successful and they develop severe negative energy balance, placing them at risk of metabolic and infectious disease and reduced fertility. We placed Holstein Friesian cows into metabolicall...
ORGANISM(S): Bos taurus 
2021-07-09 | E-MTAB-9348 | biostudies-arrayexpress
TranscriptomicsscRNA-seq of lymph node of mice where Cip2a locus has been disrupted and wild-type control mice at the peak of Experimental Autoimmune Encephalomyelis
We induced EAE in mice carrying a gene-trap disruption of Cip2a (hereafter referred to as knockout [KO] mice) and wild-type (WT) control C57BL/6J male and female mice, aged 8-12 weeks. We performed scRNA-seq analysis of lymph node cells from five WT and five KO mice at the peak of EAE. The goal was ...
ORGANISM(S): Mus musculus 
2026-09-30 | E-MTAB-17644 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human lymphocytes from 1240 Mexican Americans for the discovery of expression QTLs
Transcriptional profiles were generated for lymphocyte samples from 1,240 randomly ascertained, mostly non-diseased Mexican American participants in the San Antonio Family Heart Study. Research findings related to the genetic regulation of expression levels are published in the following article: Go...
ORGANISM(S): Homo sapiens 
2008-01-01 | E-TABM-305 | biostudies-arrayexpress
TranscriptomicsExpression of AWR5 in wild type and cdc55 deletion mutant at 6 h of induction
Expressing the type III effector AWR5 of the phytopathogen Ralstonia solanacearum in yeast cells causes cessation of growth and transcriptional changes reminiscent of inhibition of the TOR pathway. Deletion of cdc55, a regulatory subunit of the PP2A Ser/Thr protein phosphatase eliminates the strong ...
ORGANISM(S): Saccharomyces cerevisiae 
2015-12-31 | E-GEOD-70331 | biostudies-arrayexpress
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