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TranscriptomicsEffect of milk intake on circulating plasma miRNAs of adult humans
This study examines circulating plasma miRNAs of adult human subjects before and after bovine milk intake. We sought to confirm and expand findings previously reported by Baier, et al., J Nutr, 2014, PMID 25122645, using the same samples. Plasma samples were provided by the Zempleni lab (see Baier, ...
ORGANISM(S): Homo sapiens 
2016-04-06 | E-GEOD-79960 | biostudies-arrayexpress
TranscriptomicsEffect of milk intake on circulating PBMC miRNAs of adult humans
This study examines circulating PBMC miRNAs of adult human subjects before and after bovine milk intake. We sought to confirm and expand findings previously reported by Baier, et al., J Nutr, 2014, PMID 25122645, using the same samples. PBMC RNA samples were provided by the Zempleni lab (see Baier, ...
ORGANISM(S): Homo sapiens 
2016-04-06 | E-GEOD-79922 | biostudies-arrayexpress
MetabolomicsPseudomonas sp. Strain 273 Incorporates Organofluorine into the Lipid Bilayer during Growth with Fluorinated Alkanes
Anthropogenic organofluorine compounds are recalcitrant, globally distributed, and a human health concern. Although rare, natural processes synthesize fluorinated compounds, and some bacteria have evolved mechanisms to metabolize organofluorine compounds. Pseudomonas sp. strain 273 grows with...
2022-06-06 | MTBLS3893 | MetaboLights
ProteomicsAnalysis of factors bound to native metaphase ESC chromosomes following purification by flow cytometry
Stem cells are able to self-renew and also generate differentiated progeny. How gene expression patterns are transmitted through mitosis remains unresolved. Conventional studies have relied upon rigorous cell-cycle-stage synchronisation to find factors in mitotic lysates that could ‘bookmark’ the ge...
ORGANISM(S): Mus musculus (Mouse) 
2020-06-15 | PXD015251 | Pride
Mitosis Stem cells Chromosomes Chromatin 
ProteomicsHbo1 and Msl complexes preserve differential compaction and H3K27me3 marking of active and inactive X chromosomes during mitosis
In mammals, chromosome-wide regulatory mechanisms ensure a balance of X-linked gene dosage between males (XY) and females (XX). In female cells, expression of genes from one of the two X-chromosomes is curtailed, with selective accumulation of Xist-RNA, Xist-associated proteins, specific histone mod...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-23 | PXD054014 | Pride
Proteomics Mitotic Mouse Chromosomes 
MetabolomicsUntargeted metabolomics analyses and contaminant chemistry of Dreissenid mussels at the Maumee River Area of Concern in the Great Lakes

Bivalves serve as an ideal ecological indicator; hence, their use by the NOAA Mussel Watch Program to monitor environmental health. This study aimed to expand the baseline knowledge of using metabolic end points in environmental monitoring by investigating the dreissenid mussel metabolome in the ...

2024-06-03 | MTBLS6311 | MetaboLights
TranscriptomicsMicroarray of cell strain-derived induced pluripotent stem cell
Study of gene expression at passage 1 through 4 following differentiation of stem cells. Study of dengue infected and mock infected gene expression in cells at passage 1 and 4 post differentiation from induced pluripotent stem cells.
ORGANISM(S): Homo sapiens 
2021-05-27 | E-MTAB-10440 | biostudies-arrayexpress
ProteomicsH3pT11 regulates histone homeostasis and replication-coupled nucleosome assembly
newly synthesized H3 is phosphorylated at T11 by the CPC complex, licensing Asf1 binding and nuclear import; upon nuclear entry, H3pT11 facilitates Rtt109-catalyzed H3K56 acetylation, which antagonizes Hat1 and promotes nucleosome assembly by CAF-1 and Rtt106 16; subsequently, Rtt101-mediated H3K122...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2026-08-05 | PXD077347 | Pride
H3k79me3 h3t11 phosphorylation histone homeostasis 
MetabolomicsAn interoperability framework for multicentric breath metabolomic studies
Exhaled breath contains valuable information at the molecular level and offers promising potential for precision medicine. However, few breath tests transition to routine clinical practice, partly because of the missing validation in multicenter trials. Therefore, we developed and applied an interop...
2022-10-27 | MTBLS5657 | MetaboLights
ProteomicsAlprazolam abrogates TLR4 signaling and reduces inflammatory cytokine production in pancreatic cancer-associated fibroblasts
Pancreatic ductal adenocarcinoma (PDAC) diagnoses are often accompanied by a number of physical and psychological symptoms, including anxiety and depression. As a result, many patients are prescribed anxiolytics such as benzodiazepines that have unintended effects on the tumor. Previous work from ou...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD067046 | Pride
Pancreatic cancer Tmt Phosphoproteomics 
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