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MetabolomicsSponge exhalent seawater contains a unique chemical profile of dissolved organic matter
Sponges are efficient filter feeders, removing significant portions of particulate and dissolved organic matter (POM, DOM) from the water column. While the assimilation and respiration of POM and DOM by sponges and their abundant microbial symbiont communities have received much attention, there is ...
2016-02-01 | MTBLS281 | MetaboLights
MetabolomicsSAR11 Cells Rely on Enzyme Multifunctionality to Transport and Metabolize a Range of Polyamine Compounds
In the ocean surface layer and cell culture, the polyamine transport protein PotD of SAR11 bacteria is often one of the most abundant proteins detected. Polyamines are organic cations at seawater pH produced by all living organisms and are thought to be an important component of dissolved organic ma...
2021-09-09 | MTBLS3146 | MetaboLights
ProteomicsLC-MS/MS IP_DDR1 - Determine the relative abundance of proteins that associate with DDR1 when cells with different expression levels of DDR1 and lacking beta 1 integrins are cultured on collagen or on fibronectin
Determine the relative abundance of proteins that associate with DDR1 when cells with different expression levels of DDR1 and lacking beta 1 integrins are cultured on collagen or on fibronectin
ORGANISM(S): Mus musculus (Mouse) 
2017-02-03 | PXD005722 | Pride
Ddr1 Collagen Fibronectin 
ProteomicsCurcumin exerts its potential antitumor effects in a context dependent fashion
Background Clinical practice demonstrates that anticancer drug effects may strongly vary between different patients. Individual responses to drug action are potentially responsible for adverse effects such as establishment of resistance. Consequently, the understanding of response mechanisms to drug...
ORGANISM(S): Homo sapiens (Human) 
2018-06-04 | PXD008719 | Pride
Breast cancer Proteome profiling Anti-cancer drug Curcumin Co-culture Cancer-associated fibroblast 
TranscriptomicsA novel recurrent mutation in MITF predisposes to familial and sporadic melanoma
We identified a novel germline mutation of the microphthalmia-associated transcription factor (MITF - E318K). This mutation was found to be present in numerous melanoma families, as well as the general population, where its association with melanoma has a significant effect. We determined the effe...
ORGANISM(S): Homo sapiens 
2011-12-01 | E-GEOD-31269 | biostudies-arrayexpress
TranscriptomicsExpression analysis of human ex vivo cultivated urothelial carcinoma samples transduced with a trivalent adenoviral vector (Im02) for activation of the immune tumor microenvironment.
The trivalent adenoviral vector Im02 encodes the cDNAs for human 4-1BBL, IL-12 and IL-2. This vector was designed to change the immune tumor microenvironment. In this study we investigated the immune stimulating effect of Im02 on human primary urothelial cancer specimens or normal urothelium by micr...
ORGANISM(S): Homo sapiens 
2021-01-01 | E-MTAB-7623 | biostudies-arrayexpress
UnknownImatinib for melanomas harboring mutationally activated or amplified KIT arising on mucosal, acral, and chronically sun-damaged skin.
Not available
S-EPMC4878082 | biostudies-literature
TranscriptomicsPost-weaning blood transcriptomic differences between Yorkshire pigs divergently selected for residual feed intake
Global gene expression profiles of peripheral blood of 35 to 42 day-old Yorkshire pigs with extremely low (more efficient) and high RFI (less efficient) values from two Iowa State University lines (the low RFI line, n = 15, and the high RFI line, n =16) that were divergently selected for RFI during...
ORGANISM(S): Sus scrofa 
2016-01-15 | E-MTAB-4179 | biostudies-arrayexpress
TranscriptomicsExpression analysis of human ex vivo cultivated urothelial carcinoma samples transduced with a trivalent adenoviral vector (Im02) for activation of the immune tumor microenvironment.
The trivalent adenoviral vector Im02 encodes the cDNAs for human 4-1BBL, IL-12 and IL-2. This vector was designed to change the immune tumor microenvironment. In this study we investigated the immune stimulating effect of Im02 on human primary urothelial cancer specimens or normal urothelium by RNAS...
ORGANISM(S): Homo sapiens 
2020-06-18 | E-MTAB-7659 | biostudies-arrayexpress
ProteomicsNovel Kinesin Family 1A Variants Linked to Atypical Parkinsonism Elicit Altered Neuronal TDP-43 Interactions and Dendritic Atrophy
We used patient induced pluripotent stem cells (IPSC) derived neurons from a patient with two mutations in KIF1A to evaluate the quantitative changes to KIF1A protein interaction, relative to wild-type control IPSC-motor neurons, using an anti-KIF1A antibody during immunoprecipitation. Given the rel...
ORGANISM(S): Homo sapiens (Human) 
2025-08-26 | PXD067234 | Pride
Kif1a Ipsc motor neurons Tdp-43 
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