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UnknownPhase III randomized intergroup trial of CHOP plus rituximab compared with CHOP chemotherapy plus (131)iodine-tositumomab for previously untreated follicular non-Hodgkin lymphoma: SWOG S0016.
Not available
S-EPMC3732010 | biostudies-literature
ProteomicsInfluence of mutations in PPE38 on the secretome composition of M. tuberculosis
What is the influence of mutations in PPE38 on the secretome composition of M. tuberculosis? Certain clinical isolates of M. tuberculosis belonging to the Beijing lineage have mutations in ppe38 and this leads to a loss of secretion of the PE_PGRS substrates and hypervirulence in a mouse model of M....
ORGANISM(S): Mycobacterium tuberculosis 
2017-10-11 | PXD003842 | Pride
Mycobacterium tuberculosis Single-shot Label-free Ppe38 Secretome 
UnknownContinued Excellent Outcomes in Previously Untreated Patients With Follicular Lymphoma After Treatment With CHOP Plus Rituximab or CHOP Plus 131I-Tositumomab: Long-Term Follow-Up of Phase III Randomized Study SWOG-S0016.
Not available
S-EPMC6553811 | biostudies-literature
MetabolomicsHypusination Orchestrates the Antimicrobial Response of Macrophages
Innate responses of myeloid cells defend against pathogenic bacteria via inducible effectors. Deoxyhypusine synthase (DHPS) catalyzes the transfer of the N-moiety of spermidine to the lysine-50 residue of eukaryotic translation initiation factor 5A (EIF5A) to form the amino acid hypusine. Hypusinate...
2021-04-06 | MTBLS607 | MetaboLights
UnknownRecurrent Miscarriage and Implantation Failure of Unknown Cause Studied by a Panel of Thrombophilia Conditions: Increased Frequency of FXIII Val34Leu Polymorphism.
Not available
S-EPMC6486570 | biostudies-literature
TranscriptomicsLymph node T cell responses predict the efficacy of live attenuated SIV vaccines
This SuperSeries is composed of the following subset Series: GSE39967: Transcriptional profiles of unfractionated lymph nodes cells obtained from completely protected, non protected and unvaccinated control rhesus macaques seven days prior to, and four and fourteen days after wt SIVmac239 challenge ...
ORGANISM(S): Macaca mulatta 
2012-08-08 | E-GEOD-40006 | biostudies-arrayexpress
ProteomicsGeLC-MS/MS of H37Rv and two clinical isolates of Mycobacterium tuberculosis
Clinical isolates were made available from an extensive longitudinal collection of M. tuberculosis isolates circulating in the Western Cape of South Africa. Clinical isolates SAWC3651 and SAWC3517, belonging to the LAM (lineage 4.3) genotype and IS6110 family 14 and 9, respectively, and M. tubercul...
ORGANISM(S): Mycobacterium Tuberculosis (ncbitaxon:1773) 
2017-06-30 | MSV000081205 | MassIVE
ProteomicsFasciola hepatica cathepsin L zymogens: immuno-proteomic evidence for highly immunogenic zymogen-specific conformational epitopes to support diagnostics development
We conducted immuno-proteomic investigations of recombinant and native procathepsins ((r)FhpCL1) and counterpart polyclonal antibodies to a recombinant mutant procathepsin L (anti-rFhΔpCL1). Proteomics including gel electrophoresis and liquid chromatography tandem mass spectrometry were used for for...
ORGANISM(S): Fasciola hepatica (Liver fluke) 
2022-07-19 | PXD030293 | Pride
Triclabendazole. Recombinant Fasciolosis Cathepsin Diagnostics 
ProteomicsHypoxic tumor kinase signaling mediated by STAT5A in development of castration-resistant prostate cancer
To examine changes in tyrosine kinase activity in prostate cancer tumors developing resistance to androgen deprivation therapy and to compare these to changes in tyrosine kinase activity occuring in cell lines exposed to oxygen deficiency (hypoxia)
ORGANISM(S): Homo sapiens 
2013-04-15 | E-MTAB-1572 | biostudies-arrayexpress
MetabolomicsOrnithine Decarboxylase in Gastric Epithelial Cells Promotes the Immunopathogenesis of Helicobacter pylori Infection

Colonization by H. pylori is associated with a wide range of gastric diseases, ranging from superficial gastritis to more severe pathologies, including intestinal metaplasia and adenocarcinoma. The interplay of the host response and the pathogen affect the outcome of disease. One major component ...

2022-06-15 | MTBLS3235 | MetaboLights
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