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ProteomicsFKBP8 affinity mass spectrometry
Myc-FKBP8 affinity purification mass spectrometry was performed in FKBP8 knockout (KO) HEK293T and FKBP8 KO HeLa cells.
ORGANISM(S): Homo Sapiens 
2026-06-02 | PXD079162 |
ProteomicsProteomic analysis of FKBP8 knockdown in HEK293T cells
To investigate the effects of FKBP8 depletion in HEK293T cells, cells were transfected with siRNA targeting FKBP8 or with a non-targeting control siRNA for 48 hours. After transfection, cells were collected; 10% of the material was used for whole-cell proteome analysis, and the remaining 90% was use...
ORGANISM(S): Homo sapiens (Human) 
2026-03-17 | PXD070730 | Pride
Fk506-binding protein Knockdown Fkbp8 Mitochondria Hek293t 
GenomicsFKBP8 connects the Hsp70-Hsp90 chaperone machinery to the folding of membrane proteins
FKBP8 connects the Hsp70-Hsp90 chaperone machinery to the folding of membrane proteins
PRJNA1472025 | ENA
OtherFKBP8 connects the Hsp70-Hsp90 chaperone machinery to the folding of membrane proteins
The folding of membrane protein cytoplasmic domains on the endoplasmic reticulum (ER) surface, and their coordination with transmembrane and exoplasmic regions, remains poorly understood. Through a genome-wide CRISPR-Cas9 screen, we identified the ER-anchored FK506 binding protein 8 (FKBP8) as a cha...
ORGANISM(S): Homo sapiens 
2026-08-08 | GSE333678 | GEO
UnknownFKBP8 variants are risk factors for spina bifida.
Not available
S-EPMC7645715 | biostudies-literature
UnknownFKBP8 recruits LC3A to mediate Parkin-independent mitophagy.
Not available
S-EPMC5452039 | biostudies-literature
TranscriptomicsMouse Fkbp8 activity is required to inhibit cell death and establish DV patterning in the posterior neural tube
Mouse Fkbp8 mutants specifically present with spinal cord abnormalities and spina bifida. The aim is to identify gene expression changes in the posterior embryonic tissue lacking the Fkbp8 gene, so as to understand genes or gene pathways important for normal spinal cord development. Keywords: Geneti...
ORGANISM(S): Mus musculus 
2007-11-16 | GSE9604 | GEO
UnknownHepatitis C virus RNA replication is regulated by FKBP8 and Hsp90.
Not available
S-EPMC1618089 | biostudies-literature
UnknownRegulation of CLC-1 chloride channel biosynthesis by FKBP8 and Hsp90β.
Not available
S-EPMC5007535 | biostudies-literature
UnknownCharacterization of a Bcl-XL-interacting protein FKBP8 and its splice variant in human RPE cells.
Not available
S-EPMC2715170 | biostudies-literature
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