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ProteomicsPhospho-proteome analysis of PBMCs in LRRK2 mutation carriers: expansion & validation of findings of the Barcelona LRRK2 Biorepository
Supported by the Michael J Fox Foundation we established a biorepository of blood cells from G2019S LRRK2-PD patients recruited at the Hospital Clínic de Barcelona (Barcelona). Using this cohort, we performed a phospho-proteomic pilot study by mass spectrometry and identified a differential combinat...
ORGANISM(S): Homo sapiens (Human) 
2025-06-09 | PXD050944 | Pride
G2019s Phosphoproteome Lrrk2 mutations Parkinson's disease R1441g Pbmcs 
ProteomicsPhospho-proteome analysis of PBMCs in LRRK2 mutation carriers: expansion & validation of findings of the Barcelona LRRK2 Biorepository
Supported by the Michael J Fox Foundation we established a biorepository of blood cells from G2019S LRRK2-PD patients recruited at the Hospital Clínic de Barcelona (Barcelona). Using this cohort, we performed a phospho-proteomic pilot study by mass spectrometry and identified a differential combinat...
ORGANISM(S): Homo sapiens (Human) 
2025-06-09 | PXD050865 | Pride
G2019s Phosphoproteome Lrrk2 mutations Parkinson's disease R1441g Pbmcs 
TranscriptomicsTranscription profiling of human melanoma cell lines treated with 2-deoxy-5-azacytidine
Melanoma progression model:DAC-mediated gene expression
ORGANISM(S): Homo sapiens 
2007-08-25 | E-GEOD-1793 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human melanoma progression model
Melanoma progression model
ORGANISM(S): Homo sapiens 
2008-06-11 | E-GEOD-1792 | biostudies-arrayexpress
UnknownPharmacological antagonism of kainate receptor rescues dysfunction and loss of dopamine neurons in a mouse model of human parkin-induced toxicity.
Not available
S-EPMC7656261 | biostudies-literature
TranscriptomicsMicroarray analysis of RNA stability in mouse Neuro-2A cells
Microarray analysis of RNA stability in mouse Neuro-2A cells
ORGANISM(S): Mus musculus 
2011-01-24 | E-MTAB-952 | biostudies-arrayexpress
UnknownIdentification of neuronal substrates implicates Pak5 in synaptic vesicle trafficking.
Not available
S-EPMC3306725 | biostudies-literature
UnknownDifferential involvement of Ras-GRF1 and Ras-GRF2 in L-DOPA-induced dyskinesia.
Not available
S-EPMC4479526 | biostudies-literature
TranscriptomicsGene expression profiling of mouse bone marrow-derived macrophages (RNA-Seq)
Bone marrow (BM) cells were obtained by flushing the long bones of 8-week old C57BL/6 mice. BM cells were then were plated in macrophage SFM medium (Life Technologies) supplemented with penicillin-streptomycin and CSF-1 (Peprotech, 100 ng/ml) and cultured for one week to allow macrophage differenti...
ORGANISM(S): Mus musculus 
2014-11-01 | E-GEOD-58283 | biostudies-arrayexpress
TranscriptomicsTargeting ATP2B1 impairs PI3K/Akt/Forkhead box (Fox) transcription factor signaling and reduces SARS-COV-2 infection and replication
RNA-seq of human cells Edited using CRISPR vs parental and Unedited control. We identified a rare homozygous intronic variant in the ATP2B1 locus (rs111337717; chr12:89643729, T>C) that is associated with the severity of COVID-19 (i.e., symptomatic versus asymptomatic patients). Next, we employed ...
ORGANISM(S): Homo sapiens 
2024-05-13 | E-MTAB-13916 | biostudies-arrayexpress
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