Sort   by:  
 Page size 
TranscriptomicsThe viral and cellular microRNA targetome in lymphoblastoid cell lines
Epstein-Barr virus (EBV) is a human herpesvirus linked to a number of B cell cancers and lymphoproliferative disorders. During latent infection, EBV expresses 25 viral pre-microRNAs (miRNAs) and induces the expression of specific host miRNAs, such as miR-155 and miR-21, which potentially play a role...
ORGANISM(S): Homo sapiens 
2012-10-16 | E-GEOD-41437 | biostudies-arrayexpress
TranscriptomicsPlatform comparison of Affymetrix and 2 colour chips labelled with extracts derived from mice treated with Antiotensin II to induce hypertension in either a chronic or acute fashion
This study is a comparison of results from spotted 2-color cDNA arrays and Affymetrix chips using the same labeled extracts. The samples wer derived from mice in which hypertension was induced with angiotensin by an acute or chronic method.
ORGANISM(S): synthetic 
2006-09-15 | E-TIGR-122 | biostudies-arrayexpress
TranscriptomicsEvaluation of expression quantitative trait loci within two interacting blood pressure quantitative trait loci
Genetic dissection of the S rat genome has provided strong evidence for the presence of two interacting blood pressure (BP) quantitative trait loci (QTLs), termed QTL1 and QTL2, on rat chromosome 5. However, the identities of the underlying interacting genetic factors remain unknown. Further experim...
ORGANISM(S): Rattus norvegicus 
2010-06-25 | E-GEOD-7628 | biostudies-arrayexpress
TranscriptomicsA new Rrf2 repressor family member, SaiR, controls transcription of spxA2 encoding a regulator of the oxidative stress response in Bacillus anthracis.
Spx, a member of the ArsC (arsenate reductase) protein family, is highly conserved in Gram-positive bacteria, where it interacts with RNA polymerase to activate transcription in response to toxic oxidants.  In Bacillus anthracis, resistance to oxidative stress requires the activity of two paralogou...
ORGANISM(S): Bacillus anthracis 
2014-05-21 | E-GEOD-57851 | biostudies-arrayexpress
GenomicsGenome-Wide Association Study of Schizophrenia

The goal of the study is to find susceptibility genes for schizophrenia.

Dataset versioning

  • Version 1: European-American (EA) ancestry only
  • Version 2: Version 1 plus African-American (AA) ancestry

Consent groups and p...

phs000021.v3.p2 | EGA
TranscriptomicsTranscriptional profiling with a Blood Pressure QTL interval-specific oligonucleotide array
Although the evidence for a genetic predisposition to human essential hypertension is compelling, the genetic control of blood pressure (BP) is poorly understood. The Dahl salt-sensitive (S) rat is a model for studying the genetic component of BP. Using this model we previously reported the identif...
ORGANISM(S): Rattus norvegicus 
2010-06-30 | E-GEOD-1622 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of 14 regulators required for Salmonella virulene
To cause a systemic infection, Salmonella must respond to many environmental cues during mouse infection and express specific subsets of genes in a temporal and spatial manner, but the regulatory pathways are poorly established. To unravel how micro-environmental signals are processed and integrated...
ORGANISM(S): Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S 
2012-05-30 | E-GEOD-38378 | biostudies-arrayexpress
TranscriptomicsWhole-genome in vitro expression analysis of F. tularensis isolates grown to mid log phase
This study was aimed to perform comparative expression analysis of both virulent and avirulent strains of F. tularensis with a goal to possibly identify genes unique to low and high virulent strains to understand their role, if any in virulence features of an isolate. Initially, thirty strains were ...
ORGANISM(S): Francisella tularensis 
2011-02-28 | E-GEOD-26048 | biostudies-arrayexpress
GenomicGenome-Wide Association Study of Schizophrenia

The goal of the study is to find susceptibility genes for schizophrenia.

Dataset versioning

  • Version 1: European-American (EA) ancestry only
  • Version 2: Version 1 plus African-American (AA) ancestry

Consent groups and p...

phs000021 | dbGaP
MetabolomicsModel-driven multi-omic data analysis elucidates metabolic immunomodulators of macrophage activation
Macrophages are central players in immune response, manifesting divergent phenotypes to control inflammation and innate immunity through release of cytokines and other signaling factors. Recently, the focus on metabolism has been reemphasized as critical signaling and regulatory pathways of human pa...
2012-09-05 | MTBLS23 | MetaboLights
Sort   by:  
 Page size