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TranscriptomicsExpression study of the Hodgkin’s lymphoma cell line L-1236 upon CRISPR Cas9-mediated knockout of lymphotoxin alpha (LTA) compared to control
Persistent activation of canonical and non-canonical NF-κB pathways is a hallmark of the malignant Hodgkin and Reed-Sternberg cells in classical Hodgkin lymphoma (cHL). We identified lymphotoxin alpha (LTA), which is secreted by the cHL cell line L-1236 in high concentrations. This cytokine contribu...
ORGANISM(S): Homo sapiens 
2019-01-24 | E-MTAB-6896 | biostudies-arrayexpress
TranscriptomicsGene expression of T follicular helper (TFH) cells 6 h after ICOS-L blockade
The maintenance of the TFH phenotype depends on continuous signals via ICOS. For a global assessment of differences in gene expression after interruption of the ICOS pathway a genome wide transcriptome analysis was performed. We used the OT-II adoptive transfer system to isolate antigen-specific TFH...
ORGANISM(S): Mus musculus 
2015-01-19 | E-GEOD-49314 | biostudies-arrayexpress
ProteomicsStM16 standards mixture spiked into Pseudomonas aeruginosa extract
Preparation of PA14 extract spiked with StM16-Mix at different concentrations. A mixture of 16 compounds - 2-methoxybenzoic acid, biochanin A, trans-ferulic acid, 3-indoleacetonitrile, indole-3-carboxaldehyde, kinetin, p-coumaric acid, L-(+)-alpha-phenylglycine, phloridzin dihydrate, rutin trihydrat...
ORGANISM(S): Pseudomonas Aeruginosa Ucbpp-pa14 (ncbitaxon:208963) 
2025-02-26 | MSV000097219 | MassIVE
TranscriptomicsA retrotransposon-driven Dicer variant enhances endogenous RNAi in mouse oocytes
Mammals have one Dicer gene required for biogenesis of small RNAs in microRNA (miRNA) and RNA interference (RNAi) pathways. Yet, endogenous RNAi is highly active in oocytes but not in somatic cells. Here, we provide a mechanistical explanation for high RNAi activity in mouse oocytes. The main Dicer ...
ORGANISM(S): Mus musculus 
2013-11-07 | E-GEOD-41207 | biostudies-arrayexpress
no omics definedGenomic hybridization of Methanobacteria to identify the diversity in strains on manure and olive mill waste.
Population dynamics of methanogenic genera was investigated in pilot anaerobic digesters. Cattle manure and two-phase olive mill wastes were codigested at a 3:1 ratio in two reactors operated at 37 ï¾°C and 55 ï¾°C. Other two reactors were run with either residue at 37 ï¾°C. Sludge DNA extracted fro...
ORGANISM(S): Methanobacteria 
2010-11-10 | E-MEXP-2453 | biostudies-arrayexpress
UnknownStriatin is a novel modulator of cell adhesion.
Not available
S-EPMC6988865 | biostudies-literature
ProteomicsLocalization of functionally distinct CDC42 isoforms in neurons requires alternative 3'UTR usage
The proper subcellular localization of RNAs and local translational regulation is crucial in highly compartmentalized cells, such as neurons. RNA localization is mediated by specific cis-regulatory elements usually found in mRNA 3'UTRs. Therefore, processes that generate alternative 3'UTRs – alterna...
ORGANISM(S): Mus musculus (Mouse) 
2018-12-07 | PXD011518 | Pride
Cdc42 Localization Silac Isoforms 
UnknownReal-time size modulation and synchronization of a microfluidic dropmaker with pulsed surface acoustic waves (SAW).
Not available
S-EPMC5852020 | biostudies-literature
UnknownIsolation and characterisation of irinans, androstane-type withanolides from Physalis peruviana L.
Not available
S-EPMC6720484 | biostudies-literature
MetabolomicsGNPS - StM16 standards mixture spiked into Pseudomonas aeruginosa extract
Preparation of PA14 extract spiked with StM16-Mix at different concentrations. A mixture of 16 compounds - 2-methoxybenzoic acid, biochanin A, trans-ferulic acid, 3-indoleacetonitrile, indole-3-carboxaldehyde, kinetin, p-coumaric acid, L-(+)-alpha-phenylglycine, phloridzin dihydrate, rutin trihydrat...
ORGANISM(S): Pseudomonas Aeruginosa Ucbpp-pa14 (ncbitaxon:208963) 
2025-02-26 | MSV000097219 | GNPS
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