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This submission contains the mass spectrometry files for the manuscript by Filippakopoulos and colleges that characterize ZMYND8 by AP-MS and BioID. This submission contains 56 DDA files for the following baits: empty 3XFLAG control, GFP-BirA-FLAG control, NLS-BirA-FLAG control, 3xFLAG-ZMYND8 and 3x...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2015-10-01 | MSV000079336 | MassIVE
The close integration of the MAPK, PI3K, and WNT signaling pathways underpins much of development and is deregulatedin cancer. In principle, combinatorial posttranslational modification of key lineage specific transcription factors would be an effective mean stointegrate critical signaling events. U...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-12 | PXD010782 | Pride
The close integration of the MAPK, PI3K and WNT signaling pathways underpins much of development and is deregulated in cancer. In principle, combinatorial post-translational modification of key lineage–specific transcription factors would be an effective means to integrate critical signaling events....
ORGANISM(S): Mus musculus (Mouse) 
2022-02-28 | PXD010665 | Pride
Analysis of microRNA expression in vastus lateralis muscle biopsies from 11 genetically identical twin pairs discordant for type 2 diabetes. This eliminates the influence of genotype and leads to the identification of microRNAs that are exclusively influenced by environmental (non-genetic) factors. ...
ORGANISM(S): Homo sapiens 
Exercise stimulates the release of a plethora of molecules into the circulation, supporting the concept that inter-tissue signaling proteins are important mediators of adaptations to exercise. Recognising that many circulating proteins might be packaged in extracellular vesicles (EV), we employed qu...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) 
2018-01-10 | PXD006501 | Pride
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