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ProteomicsPhospho-proteomics study on FRZB-treated human retinal microvascular endothelial cells (HRECs)
Pathological neovascularization and vascular leakage are central drivers of many sight- threatening diseases. While strategies targeting vascular endothelial growth factor (VEGF) have transformed clinical outcomes, a substantial proportion of patients do not benefit from the treatment, partially att...
ORGANISM(S): Homo sapiens (Human) 
2026-03-13 | PXD073342 | Pride
Frzb Phospho-proteomics Human retinal microvascular endothelial cells 
TranscriptomicsGene expression in articular cartilage - subchondral bone of FRZB knockout mice
Objective : To study molecular changes in the articular cartilage and subchondral bone of the tibial plateau from mice deficient in frizzled related protein (Frzb) compared to wild-type mice by transcriptome analysis. Methods : Gene-expression analysis of the articular cartilage and subchondral bone...
ORGANISM(S): Mus musculus 
2012-01-12 | E-GEOD-33656 | biostudies-arrayexpress
TranscriptomicsSecreted frizzled related protein 3 (SFRP3) is required for tumorigenesis of PAX3-FOXO1-positive alveolar rhabdomyosarcoma
Alveolar rhabdomyosarcoma (aRMS) is a soft tissue sarcoma associated with the skeletal muscle lineage. The majority of aRMS tumors express the fusion protein PAX3-FOXO1 (PF), which has proven chemically intractable. As such, we identified proteins downstream from or cooperate with PF to support tu...
ORGANISM(S): Homo sapiens 
2015-12-09 | E-GEOD-67999 | biostudies-arrayexpress
TranscriptomicsGene expression in articular cartilage - subchondral bone of FRZB knockout mice
Objective : To study molecular changes in the articular cartilage and subchondral bone of the tibial plateau from mice deficient in frizzled related protein (Frzb) compared to wild-type mice by transcriptome analysis. Methods : Gene-expression analysis of the articular cartilage and subchondral bone...
ORGANISM(S): Mus musculus 
2012-01-12 | GSE33656 | GEO
UnknownFRZB: a potential prognostic marker for head and neck squamous cell carcinoma.
Not available
S-EPMC11101165 | biostudies-literature
UnknownPorcine FRZB (sFRP3) Negatively Regulates Myogenesis via the Wnt Signaling Pathway.
Not available
S-EPMC12837581 | biostudies-literature
UnknownFRZB as a key molecule in abdominal aortic aneurysm progression affecting vascular integrity.
Not available
S-EPMC7789806 | biostudies-literature
UnknownFrzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer.
Not available
S-EPMC3061830 | biostudies-literature
UnknownWnt antagonist FRZB is a muscle biomarker of denervation atrophy in amyotrophic lateral sclerosis.
Not available
S-EPMC7541525 | biostudies-literature
UnknownGenetic variants in frizzled-related protein (FRZB) and the risk of colorectal neoplasia.
Not available
S-EPMC2667207 | biostudies-literature
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