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ProteomicsN-glycoproteomics of CHO cell-expressed FGFR3
Receptor tyrosine kinases (RTKs) that undergo N-linked glycosylation undergo protein quality control in the endoplasmic reticulum (ER) and subsequently transfer to the Golgi apparatus, where they acquire a diverse array of glycan structures. The family of receptor tyrosine kinases (RTKs) known as FG...
ORGANISM(S): Homo sapiens (Human) 
2026-08-05 | PXD047309 | Pride
Fgfr3 Fibroblast growth factor receptor 3 N-glycoproteomics 
Proteomicshepatocyte grwoth factor receptor (MET) LC-MSMS
MET, the receptor for hepatocyte growth factor (HGF), is involved in wide variety of biological events and its aberrant activation is implicated in the pathogenesis of cancer. Especially, MET signaling is associated with resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor...
ORGANISM(S): Homo sapiens (Human) 
2023-04-07 | PXD029295 | Pride
Glycosylation Hepatocyte grwoth factor receptor (met) 
ProteomicsSite-specific glycan analysis of epidermal growth factor receptor 2
This study provides site-specific profiles of asparagine-linked and serine/threonine-linked glycosylations on ErbB2, a therapeutic target RTK for ErbB2-positive cancer, through structural analysis of recombinant ErbB2 extracellular region and endogenous ErbB2 from ErbB2-positive breast cancer cells....
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD039834 | Pride
Glycosylation Erbb2 Her2 
ProteomicsSite-specific glycan analysis of epidermal growth factor receptor (EGFR)
This study provides site-specific profiles of asparagine-linked and serine/threonine-linked glycosylations on ErbB2, a therapeutic target RTK for ErbB2-positive cancer, through structural analysis of recombinant ErbB2 extracellular region and endogenous ErbB2 from ErbB2-positive breast cancer cells....
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD039836 | Pride
Glycosylation Egfr 
ProteomicsSite-specific glycan analysis of CHO cell expressed epidermal growth factor receptor 2
This study provides site-specific profiles of asparagine-linked and serine/threonine-linked glycosylations on ErbB2, a therapeutic target RTK for ErbB2-positive cancer, through structural analysis of recombinant ErbB2 extracellular region and endogenous ErbB2 from ErbB2-positive breast cancer cells....
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD039835 | Pride
Glycosylation Erbb2 Her2 
ProteomicsSite-specific glycan analysis of ErbB2 in breast cancer cell BT474
This study provides site-specific profiles of asparagine-linked and serine/threonine-linked glycosylations on ErbB2, a therapeutic target RTK for ErbB2-positive cancer, through structural analysis of recombinant ErbB2 extracellular region and endogenous ErbB2 from ErbB2-positive breast cancer cells....
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD039838 | Pride
Breast cancer Erbb2 Her2 
ProteomicsSite-specific glycan analysis of ErbB2 in breast cancer cell SKBR-3
This study provides site-specific profiles of asparagine-linked and serine/threonine-linked glycosylations on ErbB2, a therapeutic target RTK for ErbB2-positive cancer, through structural analysis of recombinant ErbB2 extracellular region and endogenous ErbB2 from ErbB2-positive breast cancer cells.
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD039837 | Pride
Breast cancer Glycosylation Erbb2 Her2 
ProteomicsCINC-2 and miR-199a-5p in exosomes secreted by transplanted Thy1+ cells activate hepatocytic progenitor cell growth in rat liver regeneration
Small hepatocyte-like progenitor cells (SHPCs) are hepatocytic progenitor cells that transiently form clusters in rat livers treated with retrorsine and with 70% partial hepatectomy (PH). We previously reported that transplantation of Thy1+ cells derived from D-galactosamine-treated livers promotes ...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-04-07 | PXD039384 | Pride
Thy1 Il17rb Shpcs Kupffer cells Sinusoidal endothelial cells Lc-ms/ms 
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