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ProteomicsEpitope shaving and fungal immune evasion – cell wall proteomes
The cell wall provides a major physical interface between fungal pathogens and their mammalian host. This extracellular armour is critical for fungal cell homeostasis and survival. Yet essential cell wall moieties, such as β-1,3-glucan, are recognised as pathogen-associated molecular patterns (PAMPs...
ORGANISM(S): Candida albicans (Yeast) 
2020-06-15 | PXD018027 | Pride
Candida albicans Lc-msms Cell wall 
OtherCarbon source-induced reprogramming of the cell wall proteome and secretome modulates the adherence and drug resistance of the fungal pathogen Candida albicans
PXD ID: PXD000008. Original data file: CW1113_q1 GluLac walls rep 2.mgf. Data published as part of Proteomics 2012 12:3164-79 . From Proteomexchange: {{i}}Cell wall and secretome preparation. C. albicans RM1000 cells grown to mid-exponential phase were harvested by centrifugation. The resulting sup...
ORGANISM(S): Candida_albicans 
GPM11210010990 | GPMDB
Resource Reanalysis 
ProteomicsComparative secretome analysis of Magnaporthe oryzae identified N-glycosylation proteins involved in fungal pathogenicity and cell wall integrity
Plant fungal pathogens secrete numerous proteins into the apoplast at the plant-fungus contact sites to facilitate colonization. Only a limited number of secreted proteins have been functionally characterized in Magnaporthe oryzae, the causal agent of blast disease in rice (Oryza sativa). Intriguing...
ORGANISM(S): Magnaporthe Oryzae P131 
2021-03-12 | PXD024706 |
ProteomicsA unique cell wall synthetic response evoked by glucosamine determines pathogenicity-associated fungal cellular differentiation
The yeast-to-hypha transition is tightly associated with pathogenicity in many human pathogenic fungi, such as the model fungal pathogen Cryptococcus neoformans, which is responsible for approximately 180,000 deaths annually. In this pathogen, the yeast-to-hypha transition can be initiated by distin...
ORGANISM(S): Cryptococcus neoformans var. grubii serotype A (strain H99 / ATCC 208821 / CBS 10515 / FGSC 9487) (Filobasidiella neoformans var. grubii) 
2021-09-15 | PXD018015 | Pride
Yeast-to-hypha transition Cryptococcus neoformans Glucosamine Cell wall 
UnknownPost-transcriptional control of fungal cell wall synthesis.
Not available
S-EPMC8783092 | biostudies-literature
ProteomicsCell wall and secretome of Candida albicans WT, hir1delta/delta strain, and HIR1 complemented mutant
Cell wall and secretome of Candida albicans WT, hir1delta/delta strain, and HIR1 complemented mutant using SWATH MS.
ORGANISM(S): Candida albicans (Yeast) 
2022-02-15 | PXD018163 | Pride
Candida albicans Swath Cell wall Secretome 
ProteomicsDynamic study of the cell wall integrity signaling pathway in Aspergillus nidulans
A phosphoproteomic evaluation of the cellular response to micafungin (cell wall perturbant) in the filamentous fungi, A. nidulans, reveals putative, currently unknown cell wall integrity signaling (CWIS) associated proteins. This study used thirteen timepoints were taken from 0 to 10 minutes after c...
ORGANISM(S): Emericella nidulans (Aspergillus nidulans) 
2020-07-16 | PXD015038 | Pride
Cell wall integrity signaling Dynamic Lfq Aspergillus nidulans Micafungin Phosphoproteomics 
TranscriptomicsStimulation of dendritic cells with cell wall components
In order to dissect the response from different fungal cell wall components, monocyte-derived dendritic cells obtained from healthy donors were collected and either left untreated, or treated for four hours with either mannan, zymosan, curdlan, whole yeast, or yeast spores. This experiment is relat...
ORGANISM(S): Homo sapiens 
2012-08-28 | E-MTAB-750 | biostudies-arrayexpress
TranscriptomicsArabidopsis thaliana Growth is Negatively Regulated by the Class III Peroxidase AtPrx71 during Development and in Response to Cell Wall Damage
The cell wall is a crucial structure in plant cells, and modifications in its composition often have a major impact on growth and development. However, the molecular mechanisms responsible for the negative effects of cell wall alterations on plant growth are largely unknown. It was previously shown ...
ORGANISM(S): Arabidopsis thaliana 
2016-01-06 | E-GEOD-66980 | biostudies-arrayexpress
ProteomicsCaspofungin induced cell wall changes of Candida species influences macrophage interactions
The structure and composition of the cell walls of different Candida species alone and in response to the antifungal drug, caspofungin, were investigated. The observed differences were used to evaluate how changes at the fungal cell surface affect interactions with macrophages.
ORGANISM(S): Candida glabrata (Yeast) (Torulopsis glabrata) Candida tropicalis MYA-3404 Candida dubliniensis Candida parapsilosis Clavispora lusitaniae ATCC 42720 Meyerozyma guilliermondii ATCC 6260 
2020-05-20 | PXD019293 | Pride
Lc-msms Candida Cell wall 
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