Sort   by:  
 Page size 
ProteomicsmTOR inhibition ameliorates tau burden and neurofilament pathology in sporadic PSP-RS neurons
Progressive supranuclear palsy, Richardson’s syndrome subtype (PSP-RS), is a tauopathy marked by early axonal pathology and neurodegeneration. Modeling sporadic PSP-RS in human neurons remained a major challenge. Here, we generated midbrain dopaminergic (mDA) neurons from induced pluripotent stem ce...
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD072104 | Pride
Tauopathy  progressive supranuclear palsy  neurofilament  dopaminergic neurons  axonal degeneration  autophagy modulation 
ProteomicsCaspase inhibition restores dopaminergic identity through the PKA–CREB–BDNF axis in Parkinson’s disease neurons
The progressive loss of dopaminergic identity in midbrain neurons is a hallmark of Parkinson’s disease (PD), contributing to synaptic dysfunction and neurodegeneration. However, the molecular mechanisms linking disease-specific stress to dopaminergic transcriptional failure remain poorly understood....
ORGANISM(S): Homo sapiens (Human) 
2026-06-08 | PXD066765 | Pride
Synaptic function Parkinson’s disease Midbrain dopaminergic neurons Neurodegeneration Pka-creb pathway Apoptosis Qvd-oph 
ProteomicsPRM analysis of serum samples obtained from PCa and BPH patients
The aim of this project was the development of a predicitive model combining clinical variables and a panel of proteins measured by targeted-MS able to distinguish PCa from BPH. In particular, a total of 32 formerly N-glycosylated peptides were quantified by PRM.
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD035935 | Pride
Proteomics Serum Prm 
UnknownTranscriptome-based identification of new anti-inflammatory and vasodilating properties of the n-3 fatty acid docosahexaenoic acid in vascular endothelial cell under proinflammatory conditions [corrected].
Not available
S-EPMC4482638 | biostudies-literature
UnknownNon-Coding RNA Profile in the Progression of Carotid Atherosclerosis: A Systematic Review.
Not available
S-EPMC12842102 | biostudies-literature
UnknownEvaluation of the prognostic value of GDF-15, ABC-AF-bleeding score and ABC-AF-death score in patients with atrial fibrillation across different geographical areas.
Not available
S-EPMC7986788 | biostudies-literature
TranscriptomicsThe Antarctic Krill Euphausia superba Shows Diurnal Cycles of Transcription under Natural Conditions.
BACKGROUND: Polar environments are characterized by extreme seasonal changes in day length, light intensity and spectrum, the extent of sea ice during the winter, and food availability. A key species of the Southern Ocean ecosystem, the Antarctic krill (Euphausia superba) has evolved rhythmic physio...
ORGANISM(S): Euphausia superba 
2013-07-23 | E-GEOD-42292 | biostudies-arrayexpress
GenomicsAlzheimer's Disease Sequencing Project (ADSP)

The overarching goals of the ADSP are to: (1) identify new genomic variants contributing to increased risk of developing AD, (2) identify new genomic variants contributing to protection against developing AD, and (3) provide insight as to why individuals with known risk factor variants escape fro...

phs000572.v1.p1 | EGA
UnknownContemporary medical therapy for heart failure across the ejection fraction spectrum: The OPTIPHARM-HF registry.
Not available
S-EPMC12803666 | biostudies-literature
UnknownGlobal hospital-based disease management of acute diverticulitis: a prospective, international cohort study.
Not available
S-EPMC12512976 | biostudies-literature
Sort   by:  
 Page size