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ProteomicsSearching for interactors of endogenous SLX4
The project was aimed at identifying binding partners of endogenous SLX4 in HeLa cells. Whole cell extracts from HeLa Flp-In T-Rex cells were used for immunoprecipitation performed with anti-SLX4 antibodies from Bethyl Laboratories (A302-270A and A302-269A), either used alone or in combination. To d...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD029084 | Pride
Endogenous slx4 Interactome Lc-msms 
ProteomicsIdentifying the N-terminus of SLX4Nter in HeLa KO30 cells
The project was aimed at identifying the N-terminus of a truncated form of SLX4 (termed SLX4Nter) in HeLa KO30 cells. The HeLa KO30 cell line comes from a clone of HeLa Flp-In T-Rex cells (termed FITo) obtained through a CRISPR-Cas9 approach using commercially available plasmids from Santa Cruz Biot...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD029062 | Pride
Crispr-cas9 Slx4 N-terminus acetylation N-terminal truncation 
ProteomicsSearching for new members of the SLX4 complex and for SLX4-complex members that are SUMOylated in vitro
The project was initially aimed at identifying new members of the SLX4 complex as well as members of the complex that are SUMOylated in vitro. The project was also aimed at assessing whether SUMOylation may change the compositon of the complex by reducing complex association of SUMOylated partners. ...
ORGANISM(S): Homo sapiens (Human) 
2020-03-05 | PXD012425 | Pride
Slx4 scaffold Protein sumoylation Interactome 
TranscriptomicsTranscription profiling of human invasive and non-invasive non-functioning pituitary adenomas
Context : Non Functioning Pituitary Adenomas (NFPAs), although typically benign, may be locally invasive. Few datas are currently available related to the molecular process of invasion in sporadic pituitary adenomas. Markers of invasiveness, important for helping the clinician in the therapeutic s...
ORGANISM(S): Homo sapiens 
2010-03-18 | E-TABM-899 | biostudies-arrayexpress
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