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ProteomicsQuantitative proteomic analysis of apical interacting partners of canine galectin 8
Primary cilium is a specialized sensory organelle protruding from apical surface of most cells that transmits environmental information into cells. Its length is tightly controlled by various mechanisms such as the frequency or the cargo size of the intraflagellar transport trains which deliver the ...
ORGANISM(S): Canis familiaris (Dog) (Canis lupus familiaris) 
2023-11-25 | PXD038021 | Pride
Transition zone Primary cilia Galectin 8 Lipid raft 
TranscriptomicsTranscription profiling of human monocyte derived dendritric cells matured with Galectin-1 or LPS vs controls
Human monocyte derived dendritic cells matured via galectin-1 or LPS. Experiment Overall Design: 4 conditions with 3 replicates of each include control or intreated immature MDDCS, galectin-1 treated MDDCs, LPS treated MDDCs, and vehicle control MDDCs. (each replicate is from a distinct DONOR). Dend...
ORGANISM(S): Homo sapiens 
2007-10-26 | E-GEOD-4984 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling by array of human head and neck squamous cell carcinoma to study the correlation between galectin-1 upregulation and the presence of SMA positive cancer-associated fibroblasts
In this study, we set the presence of smooth muscle actin (SMA)-positive cancer-associated fibroblasts (CAFs) in relation to galectin-1 and its in vivo competitor (galectin-3). In squamous cell carcinomas of head and neck, upregulation of galectin-1 presence is highly significantly correlated to pre...
ORGANISM(S): Homo sapiens 
2012-11-01 | E-MTAB-850 | biostudies-arrayexpress
ProteomicsGalectin-8 facilitates B cell responses to surface-tethered antigens by promoting antigen extraction at the B cell synapse
Complete activation of B cells relies on their capacity to extract surface-tethered 35  antigens at the immune synapse by either exerting mechanical forces or promoting 36  their proteolytic degradation through lysosome secretion. Whether antigen extraction 37  can be tuned by local cues originating...
ORGANISM(S): Mus musculus (Mouse) 
2018-12-14 | PXD011522 | Pride
B-lymphocytes Processing and presentation Polarity Mouse immunization Immune synapse Antigen extraction Galectin-8 
TranscriptomicsGene expression in Galectin-3 KO vs. WT CD8 T cells
The goal of this study was to examine differences in gene expression of tumor specific CD8 T cells in an in vivo tumor mouse model after inhibition of galectin-3 protein expression by genetic knockout. Galectin-3 is thought to modulate CD8 T cell response by cross-linking cell surface glycoproteins...
ORGANISM(S): Mus musculus 
2015-02-19 | E-GEOD-59454 | biostudies-arrayexpress
TranscriptomicsGalectin-3 regulates the expression of various genes in human gastric cancer cells
Although galectin-3 is known to modulate the cell proliferation, RNA processing, tumorigenesis, metastasis and apoptosis and also, which is highly expressed in human cancers, the function of galectin-3 is still controversy in gastric cancer. Here, we demonstrated the function of galectin-3 on gastri...
ORGANISM(S): Homo sapiens 
2011-05-31 | E-GEOD-29630 | biostudies-arrayexpress
TranscriptomicsGalectin-9 suppresses growth of hepatocellular carcinoma in vitro
Galectin-9 suppresses growth of Li-7 cells, a cell line of human hepatocellular carcinoma, in vitro study. Micro RNA expression of Li-7 cells, a cell line of hepatocellular carcinoma, with or without administration of galectin-9 were assessed in vitro.
ORGANISM(S): Homo sapiens 
2015-03-01 | E-GEOD-55665 | biostudies-arrayexpress
TranscriptomicsGalectin-9 suppresses growth of hepatocellular carcinoma in vivo
Galectin-9 suppresses growth of Li-7 cells, a cell line of human hepatocellular carcinoma, in xenograft model analysis. Micro RNA expression in xenografts of Li-7 cells, a cell line of hepatocellular carcinoma, with or without administration of galectin-9 were assessed.
ORGANISM(S): Homo sapiens 
2015-03-01 | E-GEOD-55666 | biostudies-arrayexpress
GenomicsAblation of the Mammalian Lectin Galectin-8 Induces Bone Defects in Mice
Ablation of the Mammalian Lectin Galectin-8 Induces Bone Defects in Mice
PRJNA417476 | ENA
GenomicsEffect of Galectin-8 treatment on gene expression of human peripheral blood mononuclear cells
Effect of Galectin-8 treatment on gene expression of human peripheral blood mononuclear cells
PRJNA1020777 | ENA
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