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ProteomicsHuman hela cells mitochondrial LC-MS
We extracted mitochondria from Hela cells which were treated with CCCP or DMSO for 2 h. The samples were digested by FAST and peptides were used DIA to analysis.
ORGANISM(S): Homo sapiens (Human) 
2020-01-29 | PXD016400 | Pride
Mitophagy 
MetabolomicsUPLC-QTOF-MS-Based Plasma Lipidomic Profiling Reveals Biomarkers for Inflammatory Bowel Disease Diagnosis
Identification of new biomarkers may help in the early diagnosis of inflammatory bowel disease (IBD). In this study, ultrahigh-performance liquid chromatography equipped with quadrupole time-of-flight mass spectrometry (UPLC-QTOF-MS) was used to analyze the untargeted lipidomics and compare plasma l...
2021-10-18 | MTBLS1183 | MetaboLights
MetabolomicsUPLC-MS-Based Serum Metabolic Profiling Reveals Potential Biomarkers for Predicting Propofol Responsiveness in Females

Although previous studies have shown that certain factors interfere with the sensitivity of propofol, the mechanisms for interindividual variability in response to propofol remain unclear. This study aimed to screen the metabolites to predict patients' sensitivity to propofol and to identify meta...

2021-09-29 | MTBLS2311 | MetaboLights
MetabolomicsComparative analysis of proteomic and metabolomic profiles of different species of Paris

An extract prepared from species of Paris is the most widely consumed herbal product in China. The genus Paris includes a variety of genotypes with different medicinal component contents but only two are defined as official sources. Closely related species have different medicinal properties beca...

2020-01-13 | MTBLS779 | MetaboLights
ProteomicsRice Pistil LC-MSMS - Analysis of Phosphoproteome in Rice Pistil
Here we report a phosphoproteomic study on mature pistil of rice
ORGANISM(S): Oryza sativa (Rice) 
2014-07-31 | PXD000923 | Pride
Phosphorproteome Pistil Rice 
TranscriptomicsThe plasma membrane NADPH oxidase OsRbohA plays a crucial role in developmental regulation and drought-stress response in rice
Plasma membrane NADPH oxidases (NOXs) are major producers of reactive oxygen species (ROS) in plant cells under normal growth and stress conditions. Rice NOXs have multiple homologs but their functional mechanisms are largely unknown. We used microarrays to detail the global gene expression profiles...
ORGANISM(S): Oryza sativa Japonica Group 
2015-12-31 | E-GEOD-54466 | biostudies-arrayexpress
ProteomicsThe Roles of PFOA and PFOS on Human Sperm Capacitation
PFOS and PFOA are persistent organic pollutants known to impair human reproduction, but their effects and molecular mechanisms on human sperm remain unclear. Here, we conducted comprehensive proteomic and phosphoproteomic profiling of human sperm exposed to PFOS and PFOA during capacitation to provi...
ORGANISM(S): Homo Sapiens 
2025-09-28 | PXD068914 |
ProteomicsCross-link of Drosophila P75 dimer
Use XL-MS to detect whether dP75 can form homodimer
ORGANISM(S): Drosophila Melanogaster 
2024-12-12 | PXD058799 |
ProteomicsThe involvement of autophagy in mesaconitine-induced neurotoxicity in HT22 cells revealed through integrated transcriptomic, proteomic, and m6A epitranscriptomic profiling
In order to investigate the effects of mesaconitine treatment on protein expression, we carried out quantitative proteomic analysis to elucidate comprehensive protein changes in HT22 cells with or without mesaconitine treatment.
ORGANISM(S): Mus Musculus 
2024-05-03 | PXD052001 |
ProteomicsRapamycin targets RBBP7 to regulate histone H4 acetylation and suppress hepatocellular carcinoma.
Identifying therapeutic protein targets is challenging due to unpredictable druggability. Exploring multi-purpose drug targetomes, such as that of rapamycin, offers a valuable strategy for target discovery. Here, using chemical proteomics, we identified the histone-binding protein RBBP7 as a previou...
ORGANISM(S): Homo Sapiens 
2026-07-13 | PXD080960 |
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