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Proteomics2018CHPP
ABSTRACT Since 2012, Chromosome-Centric Human Proteome Project (C-HPP) launched the journey of missing proteins (MPs) investigation for completing human proteome project (HPP). We found the majority of MPs were distributed in low molecular weight (LMW) ranges, especially in 0-40 kDa. The identificat...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-14 | MSV000083978 | MassIVE
ProteomicsHuman Testis LC-MS/MS - Multi-Protease Strategy Identifies Three PE2 Missing Proteins in Human Testis Tissue
Missing proteins(MPs) investigation is one of the critical missions of Chromosome-based Human Proteome Project(C-HPP). Through analyzing sequence of MPs from neXtProt database, we found that there are no detectable tryptic peptides for some MPs. Here, we attmept a multi-enzymes strategy to cover thi...
ORGANISM(S): Homo sapiens (Human) 
2017-10-09 | PXD006465 | Pride
Testis Multi-enzymes Lc-ms/ms 
ProteomicsYeast ubiquitin ligase LC-MS/MS
Ubiquitin ligases (E3s) serves as a key regulator for ubiquitylation-mediated pathway. The identification of the corresponding relationship between E3 and its substrates is challenging but required for understanding the regulatory network of ubiquitylation. The low abundance of ubiquitinated conjuga...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2019-12-06 | PXD015654 | Pride
Hrt3 ubiquitinated substrates 
ProteomicsHuman Testis LC-MS/MS
Missing proteins(MPs) investigation is one of the critical missions of Chromosome-based Human Proteome Project(C-HPP). Through analyzing sequence of MPs from neXtProt database, we found that there are no detectable tryptic peptides for some MPs. Here, we attmept a multi-enzymes strategy to cover thi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2019-06-17 | MSV000083982 | MassIVE
ProteomicsToxicological safety evaluation of diallyl trisulfide through acute and subacute toxicity studies in ICR mice
Diallyl trisulfide (DATS) is one of the main sulfide-containing compounds in garlic oil and has been shown to have a variety of biological activities such as anti-tumor, inhibition of inflammation, and immune regulation. However, there is very little information available regarding its toxicological...
ORGANISM(S): Mus Musculus 
2024-03-28 | PXD051045 |
ProteomicsProteomic data of paeoniflorin alleviating acute hypoxic lung injury
Paeoniflorin can alleviate acute hypoxic lung injury both in vivo and in vitro. The project includes proteomic data from mouse lung tissue and HPMEC cells, as well as proteomic data for peoniflorin target screening based on Lip-MS.
ORGANISM(S): Homo Sapiens Mus Musculus 
2025-01-21 | PXD060005 |
ProteomicsProteome and phosphoproteome of erythrocyte membrane proteins in acute mountain sickness
Red blood cells are the most abundant cell type in the human body and are mainly responsible for oxygen transport. Acute altitude sickness is common in people exposed to high altitude environment, which is often accompanied by changes in the number and morphology of red blood cells. However, the rel...
ORGANISM(S): Homo Sapiens 
PXD054572 |
ProteomicsSubstrates identification of yeast Ubp2 through DILUS
SILAC-based substrates identification of yeast Ubp2
ORGANISM(S): Saccharomyces Cerevisiae 
2020-02-03 | PXD017357 |
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