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ProteomicsLabel-free proteomic analysis of apoptotic, necrotic and necroptotic DAMPs from HNSCC cells
Necroptosis is a newly discovered form of programmed cell death (PCD) showing necrotic features, including membrane permeabilization and the release of damage-associated molecular patterns (DAMPs). Studies have revealed both its tumorigenic role and therapeutic potential in various cancers, yet its ...
ORGANISM(S): Homo Sapiens 
PXD035379 |
ProteomicsNeuroprotective Effects of Desert Organic Milk Exosomes Against LPS-Induced Cognitive Impairment: Involvement of Microglial M2 Polarization and AMPK Signaling
Hippocampal neuroinflammation (HNF) is a key pathological feature in neurodegenerative disorders. Milk-derived exosomes are bioactive extracellular vesicles, yet their potential to regulate neuroinflammatory responses in the brain remains underexplored. This study aimed to characterize the superior ...
ORGANISM(S): Bos Taurus 
2025-12-11 | PXD071863 |
ProteomicsSerum proteome profiling provides a deep understanding of the “gut–liver axis” in relation to liver injury and regeneration
The gut–liver axis is one of the major contributors to the transport of products from the intestine or intestinal microbes with the progression of liver regeneration. However, the influence of proteins from the hepatic portal vein (HPV), the bridge of enterohepatic circulation, on liver regeneration...
ORGANISM(S): Mus Musculus 
2020-05-15 | PXD019212 |
ProteomicsValidation of Serotransferrin in the Serum as Candidate Biomarkers for the Diagnose of Pulmonary Tuberculosis by Label-free LC/MS
Label-free LC/MS profiles of neutrophils from 15 active TB patients and 15 healthy controls
ORGANISM(S): Homo Sapiens 
2022-04-28 | PXD033563 |
ProteomicsProteomic identification of new diagnostic biomarkers of early-stage cutaneous mycosis fungoides
Primary cutaneous T-cell lymphoma (CTCL) is responsible for two-thirds of cutaneous lymphoma cases. Mycosis fungoides (MF), the most common subtype of CTCL comprises approximately 60% of CTCLs. Due to the similar clinical features of MF and inflammatory diseases such as eczema and psoriasis, early-s...
ORGANISM(S): Homo Sapiens 
2020-11-28 | PXD022798 |
ProteomicsSpatially region resolved proteomic map reveals extracellular matrix regulates epidermal growth and function as epidermal stem cell niche
Spatial proteins expression is critical to identify exactly protein localization and function in tissues. By combining decellularization, laser-capture microdissection, and mass spectrometry, six different partitioned proteins among skin layers of stratum corneum (SC), granular-spinous (GS), basal l...
ORGANISM(S): Homo Sapiens 
2021-07-05 | PXD027093 |
ProteomicsApplication of an iPSC-derived Organoid Model for Located Scleroderma Therapy
Scleroderma is a chronic connective tissue disease characterized by skin thickening and plaque morphea, as well as hard, shiny skin. Serious involvement is observed from the superficial dermis down to the fascia and muscle. However, this condition is difficult to treat and evaluate. In this study, i...
ORGANISM(S): Mus Musculus 
PXD025613 |
ProteomicsDelaying aging and enhancing repair of the aged CNS myelin by β-NMN requires SIRT2
Myelin aging is a driving force of CNS aging, and age-dependent declined efficiency of remyelination caused by impaired differentiation capacity of aged oligodendrocyte precursor cell (OPC) is a major cause of demyelinated diseases. Revealing how differentiation capacity of aged OPC is affected meta...
ORGANISM(S): Rattus Norvegicus 
2020-10-18 | PXD022046 |
ProteomicsThe pan-cancer lncRNA PLANE regulates an alternative splicing program and promotes cancer pathogenesis
Proteome analysis of Biotin- PLANE pull-down assays
ORGANISM(S): Homo Sapiens 
2020-11-26 | PXD022747 |
UnknownRobust estimation of bacterial cell count from optical density.
Not available
S-EPMC7499192 | biostudies-literature
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