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Alternative pre-mRNA splicing has long been proposed to greatly contribute to proteome complexity. However, the extent to which mature mRNA isoforms are successfully translated into protein remains controversial. Here, we used high-throughput RNA sequencing and mass spectrometry (MS)-based proteomic...
ORGANISM(S): Homo sapiens (Human) 
2019-10-14 | PXD012556 | Pride
Epigenetics and Alternative Splicing are both critical mechanisms guiding gene expression. Several studies have demonstrated that epigenetic marks can influence alternative splicing decisions, but less is known about how alternative splicing may impact epigenetics. Here...
ORGANISM(S): Homo sapiens (Human) 
2023-02-18 | PXD036471 | Pride
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