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TranscriptomicsExpression data from P14 TCR cytotoxic T cells overexpressing HDAC7 phosphorylation deficient mutant
The present study reports an unbiased analysis of the cytotoxic T cell serine-threonine phosphoproteome using high resolution mass spectrometry. Approximately 2,000 phosphorylations were identified in CTLs of which approximately 450 were controlled by TCR signaling. A significantly overrepresented g...
ORGANISM(S): Mus musculus 
2011-03-13 | E-GEOD-27092 | biostudies-arrayexpress
ProteomicsAlternative Splicing of HDAC7 Regulates its Interaction with 14-3-3 Proteins to Alter Histone Marks and Target Gene Expression
Epigenetics and Alternative Splicing are both critical mechanisms guiding gene expression. Several studies have demonstrated that epigenetic marks can influence alternative splicing decisions, but less is known about how alternative splicing may impact epigenetics. Here...
ORGANISM(S): Homo sapiens (Human) 
2023-02-18 | PXD036471 | Pride
Nanolc-ms/ms Cd28 Cd69 Histone ptm Apoptosis Epigenetics Hdac7 
TranscriptomicsDifferential Gene Expression in HDAC7-Deficient and Transgenic Thymocytes
Title of Publication: Histone Deacetylase 7 Regulates Cell Survival and TCR Signaling in CD4/CD8 Double-Positive Thymocytes Abstract of publicaton: CD4/CD8 double-positive (DP) thymocytes express the transcriptional repressor Histone Deacetylase 7 (HDAC7), a class IIa HDAC that is exported from the ...
ORGANISM(S): Mus musculus 
2011-04-06 | E-GEOD-26488 | biostudies-arrayexpress
GenomicsHDAC7 KO sequencing
HDAC7 KO
PRJEB111931 | ENA
TranscriptomicsDNA microarrays (time course) of MEFs transduced with SKO plus HDAC7 or MEF2C
Overexpression HDAC7 can enhance iPS efficiency in SKO by supressing MEF2 factors We used microarrays to identify changes induced by overexpression of HDAC7 or MEF2C. MEFs were transduced with SKO plus HDAC7 or MEF2C compared to SKO plus empty vector(Flag), GFP as controls. TRIZOL cell lysates were ...
ORGANISM(S): Mus musculus 
2011-08-17 | E-GEOD-23692 | biostudies-arrayexpress
GenomicsHDAC7 KO - Histone acetylation ChIP-sequencing
Histone H3K9K14 acetylation ChIP-sequencing of HDAC7 KO mice
PRJEB111947 | ENA
GenomicsThe HDAC7-TET2 epigenetic axis is essential during early B lymphocyte development
The HDAC7-TET2 epigenetic axis is essential during early B lymphocyte development
PRJNA721200 | ENA
UnknownHistone deacetylase 7 (HDAC7) regulates myocyte migration and differentiation.
Not available
S-EPMC2922493 | biostudies-literature
UnknownHDAC7 promotes ovarian cancer malignancy via AKT/mTOR signalling pathway.
Not available
S-EPMC11491867 | biostudies-literature
TranscriptomicsGene Regulation by HDAC7 in Thymic Selection
Histone deacetylase 7 (HDAC7) is highly expressed in CD4+/CD8+ thymocytes and functions as a signal-dependent repressor of gene transcription during T cell development. In this study, we express HDAC7 mutant proteins in a T cell line and use DNA microarrays to identify transcriptional targets of HDA...
ORGANISM(S): Mus musculus 
2007-11-04 | GSE7468 | GEO
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