Sort   by:  
 Page size 
ProteomicsChanges in the Membrane-Associated Proteins of Exosomes Released from Human Macrophages after Mycobacterium tuberculosis Infection - Biotinylated
Tuberculosis (TB) is the deadliest infectious disease worldwide. One obstacle hindering the elimination of TB is our lack of understanding of host-pathogen interactions. Exosomes, naturally loaded with microbial molecules, are circulating markers of TB. Changes in the host protein composition of exo...
ORGANISM(S): Homo sapiens (Human) 
2018-08-06 | PXD010659 | Pride
Biotin Asp-n 
MetabolomicsMetabolic Drug Response Phenotyping in Colorectal Cancer Organoids by LC-QTOF-MS
As metabolic rewiring is crucial for cancer cell proliferation, metabolic phenotyping of patient-derived organoids is desirable to identify drug-induced changes and trace metabolic vulnerabilities of tumor subtypes. We established a novel protocol for metabolomic and lipidomic profiling of colorecta...
2021-10-12 | MTBLS2130 | MetaboLights
UnknownDifferential Item Functioning and Clinical Utility of the Subjective Memory Complaints Questionnaire in a Multi-Ethnic Cohort.
Not available
S-EPMC11930848 | biostudies-literature
TranscriptomicsOxidized mitochondrial nucleoids released by neutrophils drive type I Interferon production in human lupus
Autoantibodies against nucleic acids and excessive type I Interferon (IFN) are hallmarks of human Systemic Lupus Erythematosus (SLE). We previously reported that SLE neutrophils, exposed to TLR7-agonist autoantibodies, release interferogenic DNA, which we now demonstrate to be of mitochondrial or...
ORGANISM(S): Homo sapiens 
2016-04-07 | E-GEOD-78243 | biostudies-arrayexpress
ProteomicsProteome changes as consequence of altered c-di-GMP metabolism in BCG
Pellicles, a type of biofilm, have gathered a renewed interest in the field of tuberculosis as a structure that mimics some characteristics occurring during M. tuberculosis infection, such as antibiotic recalcitrance and chronicity of infection. In other bacteria, it has been well documented that th...
ORGANISM(S): Mycobacterium bovis BCG str. Pasteur 1173P2 
2018-03-21 | PXD005894 | Pride
C-di-gmp Mycobacteria Pellicle Proteome 
TranscriptomicsMolecular Characterization of Spontaneously Transformed Epithelial Murine Colon Cell Lines as a Model of Human Colorectal Neoplasia (CGH)
To characterize a series of mouse colon cells that have become spontaneously transformed over time in order to identify the chromosomal and genomic alterations that take place during the development of tumorigenesis. Colorectal cancer is the third common malignancy in the United States. The stepwise...
ORGANISM(S): Mus musculus 
2016-07-03 | E-GEOD-70790 | biostudies-arrayexpress
TranscriptomicsAneuploidy, oncogene amplification, and epithelial to mesenchymal transition define spontaneous transformation of murine epithelial cells [CGH]
Human epithelial cancers are defined by a recurrent distribution of specific chromosomal aneuploidies. In our model system, mouse bladder and kidney epithelial cells spontaneously immortalize, transform and become tumorigenic after prolonged culture. We assessed genome and transcriptome alterations...
ORGANISM(S): Mus musculus 
2013-03-14 | E-GEOD-45128 | biostudies-arrayexpress
UnknownImmune persistence and safety of the AS01<sub>E</sub>-adjuvanted respiratory syncytial virus prefusion F protein-based vaccine in adults 50-59 years of age, including at-increased-risk adults: A randomized controlled trial.
Not available
S-EPMC12599337 | biostudies-literature
UnknownNoninferior Immunogenicity and Consistent Safety of Respiratory Syncytial Virus Prefusion F Protein Vaccine in Adults 50-59 Years Compared to ≥60 Years of Age.
Not available
S-EPMC11478578 | biostudies-literature
TranscriptomicsDNA copy number changes in colorectal flat adenomas
Background & aim: Flat adenomas form a specific phenotype of colorectal adenomas that has been associated with more severe molecular changes and consequently a more aggressive clinical behavior compared to their polypoid counterparts. In the present study we set out to compare one of the molecular c...
ORGANISM(S): Homo sapiens 
2012-10-04 | E-GEOD-30479 | biostudies-arrayexpress
Sort   by:  
 Page size