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ProteomicsYeast - phosphoproteome - Yeast PP4 Interacts with ATR Homolog Ddc2-Mec1 and Regulates Checkpoint Signaling
To find the Mec1 targets that are responsible for mec1-100 suppression on HU, we performed a quantitative phosphoproteomic study. Specifically, we screened for modifications that are downregulated in mec1-100, compensated by pph3delta, and left unaffected by rad53delta. To eliminate contributions fr...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2015-01-12 | PXD001492 | Pride
S. cereviasiae 
ProteomicsSarcoptes scabiei ES proteomics
Background: The parasitic mite Sarcoptes scabiei is an economically highly significant parasite of the skin of humans and animals worldwide. This mite causes a neglected tropical disease (NTD), called scabies - one of the commonest dermatological problems globally, resulting in major morbidity, disa...
ORGANISM(S): Sarcoptes scabiei 
2020-09-08 | PXD016925 | Pride
I es proteomics Es Lc-ms/ms 
UnknownWhole-genome sequence of the bovine blood fluke Schistosoma bovis supports interspecific hybridization with S. haematobium.
Not available
S-EPMC6361461 | biostudies-literature
TranscriptomicsGenome-wide localization of Ino80 and Arp5 on chromosome in Saccharomyces cerevisiae
Background: Chromatin remodeling complexes facilitate the access of enzymes that mediate transcription, replication or repair of DNA by modulating nucleosome position and/or composition. Ino80 is the DNA-dependent Snf2-like ATPase subunit of a complex whose nucleosome remodeling activity requires ac...
ORGANISM(S): Saccharomyces cerevisiae 
2008-04-10 | E-GEOD-9233 | biostudies-arrayexpress
UnknownInteraction of Human ACE2 to Membrane-Bound SARS-CoV-1 and SARS-CoV-2 S Glycoproteins.
Not available
S-EPMC7601831 | biostudies-literature
TranscriptomicsTranscription profiling of Pichia pastoris strain GS115 transformed with the empty vector pGAPHIS or consitutively overproducing the activated form of S. cerevisiae Hac1
Strain GS115 transformed with the empty vector pGAPHIS (a histidine prototrophic isogenic strain of GS115) was compared to Strain GS115 HAC1, constitutively overproducing the activated form of S. cerevisiae Hac1
ORGANISM(S): Pichia pastoris 
2008-09-23 | E-MEXP-1616 | biostudies-arrayexpress
TranscriptomicsGenome-wide localization of Ino80 on chromosome in Saccharomyces cerevisiae
Background: Chromatin remodeling complexes facilitate the access of enzymes that mediate transcription, replication or repair of DNA by modulating nucleosome position and/or composition. Ino80 is the DNA-dependent Snf2-like ATPase subunit of a complex whose nucleosome remodeling activity requires ac...
ORGANISM(S): Saccharomyces cerevisiae 
2008-04-10 | E-GEOD-9420 | biostudies-arrayexpress
UnknownMetallodrug Profiling against SARS-CoV-2 Target Proteins Identifies Highly Potent Inhibitors of the S/ACE2 interaction and the Papain-like Protease PLpro.
Not available
S-EPMC8653295 | biostudies-literature
UnknownThe FRESH Study: Treatment of Intracranial Aneurysms with the New FRED X Flow Diverter with Antithrombotic Surface Treatment Technology-First Multicenter Experience in 161 Patients.
Not available
S-EPMC10084892 | biostudies-literature
ProteomicsRegulatory phosphosite on Mec1 and control of RNAP11 and PIII during replication stress
Yeast sensor checkpoint kinase Mec1 is phosphorylated at Ser1991 upon HU replication stress. The phospho-accepter mutant (mec1-S1991A) confers HU sensitivity and synthetic sickness with the mutants that aggravate replication and transcription collision. To understand how the entire chromatin proteom...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-09-28 | PXD027337 | Pride
Lc-msms Mec1 Yeast Chromatome Phosphoproteomics Replication stress 
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