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TranscriptomicsTranscription profiling by array of HC11 mammary epithelial cell strains stably expressing different variants of the transcriptional regulator megakaryoblastic leukemia-1 (Mkl1)
We have previously shown that HC11 mammary epithelial cells react strongly to the overexpression of megakaryoblastic leukemia-1 (Mkl1) with induction of tenascin-C expression. The present study was designed to find genes co-regulated with tenascin-C by Mkl1 in a SAP domain-dependent manner and witho...
ORGANISM(S): Mus musculus 
2014-02-06 | E-GEOD-44907 | biostudies-arrayexpress
ProteomicsActinomycin targets NPM1c-primed mitochondria in AML
Acute myeloid leukemia (AML) pathogenesis often involves a mutation in the NPM1 nucleolar chaperone, but the bases for its transforming properties and association with favorable outcome remain incompletely understood. Here we demonstrate that an oncogenic mutant form of NPM1 (NPM1c) hampers formatio...
ORGANISM(S): Homo sapiens (Human) 
2021-12-17 | PXD025507 | Pride
Pml Lfq Actinomycin d Mitochondria Npm1c Qexactive Senescence 
UnknownFLT3L-dependent dendritic cells control tumor immunity by modulating Treg and NK cell homeostasis.
Not available
S-EPMC10772324 | biostudies-literature
UnknownDisruption of Glut1 in Hematopoietic Stem Cells Prevents Myelopoiesis and Enhanced Glucose Flux in Atheromatous Plaques of ApoE(-/-) Mice.
Not available
S-EPMC4824305 | biostudies-literature
UnknownTNF/TNFR1 is a Key Regulator of Prolonged Fasting-Induced Decrease in Adipose Tissue.
Not available
S-EPMC12784137 | biostudies-literature
TranscriptomicsComparison of gene expression profiles between human and mouse monocyte subsets [human data]
Human and mouse blood each contain two monocyte subsets. Here, we investigated the extent of their similarity using a microarray approach. Approximately 300 genes in human and 550 genes in mouse were differentially expressed between subsets. More than 130 of these gene expression differences were co...
ORGANISM(S): Homo sapiens 
2009-12-07 | E-GEOD-18565 | biostudies-arrayexpress
UnknownLysosomal Cholesterol Hydrolysis Couples Efferocytosis to Anti-Inflammatory Oxysterol Production.
Not available
S-EPMC6034181 | biostudies-literature
UnknownEarly activation of the cardiac CX3CL1/CX3CR1 axis delays β-adrenergic-induced heart failure.
Not available
S-EPMC8429682 | biostudies-literature
UnknownA tunable and versatile chemogenetic near-infrared fluorescent reporter.
Not available
S-EPMC11911394 | biostudies-literature
TranscriptomicsTranscriptome analysis reveals regulatory networks underlying differential susceptibility to Botrytis cinerea in response to nitrogen availability in Solanum lycopersicum.
Transcriptomic analysis in response to Botrytis cinerea infections under conrasting nitrate regime Nitrogen (N) is one of the main limiting nutrients for plant growth and crop yield. It is well documented that changes in nitrate availability, the main N source found in agricultural soils, influences...
ORGANISM(S): Solanum lycopersicum 
2015-09-16 | E-GEOD-73006 | biostudies-arrayexpress
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