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Genomic content of Vaccine strains were probed against the known sequence of the virulent strain Rlow of M. gallisepticum to identify divergent or absent genes in the attenuated strains. Genomic DNA was extracted from in vitro grown cultures of M. gallisepticum strains Rlow, F, ts-11, and 6/85 and t...
ORGANISM(S): Mycoplasma gallisepticum 
n patients with PMF, excessive secretion of inflammatory cytokines results in fibrotic changes in bone marrow and diminishes the quality of life of the affected patients due to systemic symptoms long-term ruxolitinib therapy may reverse or markedly delay BM fibrosis progression in advanced MF sugge...
ORGANISM(S): Homo sapiens (Human) 
2023-05-18 | PXD027250 | Pride
THOC5, a member of the THO complex, is essential for the 3´processing of some inducible genes, the export of a subset of genes and stem cell self-renewal. Utilising nanopore mRNA-sequencing we show that when THOC5 is depleted 50% of mRNAs undergo altered 3´end cleavage. Further, THOC5 depletion lead...
ORGANISM(S): Homo sapiens (Human) 
2022-12-12 | PXD035092 | Pride
TARGET (Tumour characterisation to Guide Experimental Targeted therapy) seeks to optimise the pathway for molecular characterisation of all patients entering early phase cancer trials to inform clinical decision-making on optimal therapy. Performance status (PS) was developed to assess a patient’s a...
ORGANISM(S): Homo sapiens (Human) 
2022-07-05 | PXD023553 | Pride
Investigation into PSP using proteomic techniques. Through the use of different human brain preps, the differences between those with Progressive supranuclear palsy and those without will be compared
ORGANISM(S): Homo sapiens (Human) 
2025-08-25 | PXD047282 | Pride
Adult hippocampal neurogenesis is involved in key cognitive phenomena, such as memory and learning, mood regulation, stress and anxiety. In postmortem human patients, adult neurogenesis has been shown to decrease in correlation with Alzheimer’s disease and mild cognitive decline. Thus, therapies aim...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD066537 | Pride
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