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TranscriptomicsNCI-H1299 lung cancer cell line transfected with miR-34a and ghR-34a
Analysis NCI-H1299 lung cancer cells transfected with synthetic oligo mimics for microRNAs (miRNAs) miR-34a and ghR-34a. We developed a 30-nucleotide single-strand RNA (ssRNA), termed “guide hairpin RNA (ghR),” that has a physiological function similar to that of miRNA and siRNA. The ghR caused no i...
ORGANISM(S): Homo sapiens 
2015-07-29 | E-GEOD-71423 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse livers from growth hormone receptor (GHR) deficient mice and mice expressing different forms of truncated GHR to study the GHR signaling domains and their associated transcripts.
Total RNA was extracted from mouse liver samples using an Ambion RNaqueous RNA extraction kit. Targets were produced using modified Affymetrix procedure from 5ug of total RNA. 3 biological replicates were analysed per each group of animals.
ORGANISM(S): Mus musculus 
2007-12-13 | E-GEOD-988 | biostudies-arrayexpress
GenomicsTamoxifen-induced Ghr deletion in WT mouse prostates
Tamoxifen-induced Ghr deletion in WT mouse prostates
PRJNA811433 | ENA
ProteomicsMolecular data integration reveals Growth Hormone Receptor as an alternative candidate oncogenic signaling pathway in glioblastoma
Our laboratory has identified the Growth Hormone Receptor (GHR) as a candidate oncogenic pathway involved in GBM oncogenicity. In order to study further the role of GHR in GBM, we have generated GHR overexpressing patient-derived cell lines (PDCL) from PDCL established by GlioTEx team (Institut du ...
ORGANISM(S): Homo sapiens (Human) 
2022-06-23 | PXD004969 | Pride
Glioblastoma Socs2 Gains of function Proteomic Egfr Expression array Ghr Cellular movement 
UnknownChicken GHR natural antisense transcript regulates GHR mRNA in LMH cells.
Not available
S-EPMC5342002 | biostudies-literature
GenomicsTamoxifen-induced Ghr deletion in SV40 C3(1) T-antigen mouse prostates
Tamoxifen-induced Ghr deletion in SV40 C3(1) T-antigen mouse prostates
PRJNA811573 | ENA
TranscriptomicsNCI-H1299 lung cancer cell line transfected with miR-34a and ghR-34a
Analysis NCI-H1299 lung cancer cells transfected with synthetic oligo mimics for microRNAs (miRNAs) miR-34a and ghR-34a. We developed a 30-nucleotide single-strand RNA (ssRNA), termed “guide hairpin RNA (ghR),” that has a physiological function similar to that of miRNA and siRNA. The ghR caused no i...
ORGANISM(S): Homo sapiens 
2015-07-29 | GSE71423 | GEO
ProteomicsHolistic proteome analyses of heart samples from GHR-deficient (GHR-KO) pigs
A proteomics analysis of heart samples from GH receptor deficient (GHR-KO) pigs has been performed. This animal model is unique to study consequences of lacking GH actions. In this study, we used LC-MS/MS to capture alterations in the heart proteome of this clinically relevant large animal model.
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2020-12-01 | PXD019852 | Pride
Growth hormone  laron syndrome  heart  pig model  proteomics 
TranscriptomicsTamoxifen-induced Ghr deletion in WT mouse prostates
Two-month old tamoxifen-inducible Ghr recombination mice (Ghrflox/flox;ROSA26Cre-ERT2+/0) or tamoxifen-control mice (Ghrflox/flox) were treated with 250 mg/kg tamoxifen for five straight days. The dorsolateral prostate of each mouse was collected one month after final treatment and RNA was collected...
ORGANISM(S): Mus musculus 
2023-01-01 | GSE197640 | GEO
UnknownIdentification and characterization of GHR gene promoter of yak.
Not available
S-EPMC12764550 | biostudies-literature
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