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Proper assembly of complex neural circuits requires the coordinated action of a limited set of axon guidance molecules, including plexins. To probe the extracellular vicinity of PlxnA2 in primary hippocampal neurons, we used in this work antibody directed proximity biotinylation and identified cand...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-16 | PXD060323 | Pride
Our data support that following optic nerve crush injury, ocular infiltration of immune cells causes damage to the retinal vasculature and compromises the integrity of the blood-retina barrier (BRB). Functional ablation of integrin alphaM (CD11b) attenuates immune cell trafficking, protects the BRB,...
ORGANISM(S): Mus musculus (Mouse) 
2026-08-05 | PXD045885 | Pride
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