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ProteomicsImmunoprecipitation and Mass Spectrometry Reveals Interactors of CD11b
We aimed to identify CD11b-associated inhibitory receptors,that control phagocytosis when engaged by ligands expressed on cancer cells. CD11b was immunoprecipitated from mouse bone marrow-derived macrophages (BMDMs), and the associated proteins were analyzed using mass spectrometry. A few inhibitory...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-17 | PXD063540 | Pride
Mac-1 Cd200r1 Cd11b Bmdms 
TranscriptomicsTranscription profiling of mouse FLT3+/CD11b+ Dendritic cell (DC) progenitor
FLT3+/CD11b+ Dendritic cell (DC) progenitor was amplified in vitro from mouse bone marrow.
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-692 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse CD11b cells purified from mouse spleen from umor-free and tumor-bearing mice
Active suppression of tumor-specific T lymphocytes can limit the immune-surveillance and immunotherapy efficacy. While tumor-recruited CD11b+ myeloid cells are known mediators of tumor-associated immune dysfunction, the true nature of these suppressive cells and the fine biochemical pathways governi...
ORGANISM(S): Mus musculus 
2009-04-29 | E-GEOD-5455 | biostudies-arrayexpress
TranscriptomicsExpression profiling of murine E10.5 TLR2+ CD11b+ embryonic phagocytes by comparative microarray analyses
The detection of Toll-like receptor 2 (TLR2) expression on E10.5 early embryonic phagocytes prompted us to determine the list of markers co-expressed with TLR2 in a cell-type specific manner. Thus, a comparative expression profiling of cDNAs between murine E10.5 TLR2+ CD11b+ embryonic cells and TLR2...
ORGANISM(S): Mus musculus 
2014-12-01 | E-MTAB-1537 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of CX3CR1high CD11b+ CD11c+ cells in murine intestinal lamina propria
Several innate immune cell subsets have recently been identified to maintain gut homeostasis in both human and mice. Among these subsets, CX3CR1high CD11b+ CD11c+ cells contribute to intestinal tolerance through various mechanisms in mice. However, whether tolerogenic innate myeloid cells are presen...
ORGANISM(S): Mus musculus 
2016-07-17 | E-GEOD-79628 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse natural killer (NK) cell subsets defined by CD27 and CD11b expression
Previous reports have defined three subsets of mouse NK cells on the basis of the expression of CD27 and CD11b. The developmental relationship between these subsets was unclear. To address this issue, we evaluated the overall proximity between mouse NK cell subsets defined by CD27 and CD11b expressi...
ORGANISM(S): Mus musculus 
2009-03-21 | E-GEOD-13229 | biostudies-arrayexpress
ProteomicsCharacterization of MACS isolated microglia cells (CD11b positive cells) in comparison to all non-CD11b positive cells (termed non-target cell fraction (NTCF)) with proteomics
Microglia isolation from adult mouse brains remains difficult in comparison to microglia isolation from brains from newborn mouse brains as connective tissue, extracellular matrix materials and thicker myelin sheaths substantially influence traditional isolation protocols used with newborn mouse bra...
ORGANISM(S): Mus musculus (Mouse) 
2024-03-22 | PXD031973 | Pride
Cd11b positive cells Proteomics Microglia Ntcf 
TranscriptomicsTranscription profiling of mouse dendritic cells from Flt3+CD11b+ progenitors in vitro
Assessing the gene expression repertoire of antigen presenting dendritic cells
ORGANISM(S): Mus musculus 
2008-06-15 | E-GEOD-702 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse dendritic cell differentiation from dendritic cell progenitor in vitro
FLT3+CD11b+ DC progenitor was amplified in vitro from mouse bone marrow. DC were differentiated using GM-CSF and analyzed at day 7 and day 10 of differentiation and after 16h TNFalpha stimulation at day 10
ORGANISM(S): Mus musculus 
2008-06-14 | E-GEOD-575 | biostudies-arrayexpress
ProteomicsCD11b restricts alveolar macrophage activation during pneumococcal pneumonia and prevents excessive lung inflammation
Bacterial lung infections are associated with strong infiltration of CD11b+ myeloid cells, which limit life-threatening disease, but also severely damage lung tissue. In a murine lung infection model with Streptococcus pneumoniae, we found intrinsic upregulation of CD11b on resident alveolar macroph...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-08 | PXD035269 | Pride
Streptococcus pneumoniae Alveolar macrophages Integrin α-m 
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