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Project Description (Revised): CD200R1 inhibits phagocytosis through its intracellular tyrosine residues Y286 and Y297. To investigate whether these residues recruit inhibitory molecules, we performed pull-down assays using synthetic peptides—either phosphorylated or unphosphorylated—corresponding t...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-17 | PXD063538 | Pride
Characterization od swine CD200R1 splicing variants expressed in blood monocytes
Characterization of porcine CD200R1-like splicing variants expressed in blood monocytes
CD200R1 loss in CNS-associated macrophages triggers T cell-driven neurodegeneration in Parkinson’s disease
Immune dysregulation is increasingly recognized as a key contributor to Parkinson’s disease (PD) pathogenesis. While microglia are established central nervous system (CNS) immune regulators, the role of CNS-associated macrophages (CAMs) and their upstream modulation by immune checkpoints remains poo...
ORGANISM(S): Mus musculus 
2025-08-09 | GSE304505 | GEO
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