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We aimed to identify CD11b-associated inhibitory receptors,that control phagocytosis when engaged by ligands expressed on cancer cells. CD11b was immunoprecipitated from mouse bone marrow-derived macrophages (BMDMs), and the associated proteins were analyzed using mass spectrometry. A few inhibitory...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-17 | PXD063540 | Pride
To identify potential regulators involved in virus-triggered innate immune response, we used tandem mass tagging (TMT)-based shotgun proteomic analysis of murine bone marrow-derived macrophages (BMDMs) following sendai virus (SeV) infection. This approach facilitated the identification and relative ...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-03 | PXD051098 | Pride
Reticuloendothelial macrophages engulf ~0.2 trillion senescent erythrocytes daily in a process called erythrophagocytosis (EP). This critical mechanism preserves systemic heme-iron homeostasis by regulating red blood cell (RBC) catabolism and iron recycling. Although extensive work has demonstrated ...
ORGANISM(S): Mus musculus (Mouse) 
2020-05-27 | PXD017788 | Pride
NGS5439 - BMDMs cytokine response
To recruit phagocytes, apoptotic cells characteristically release ATP, which functions as a “danger” signal. Here, we found that the culture supernatant of apoptotic cells activated the macrophages to express anti-inflammatory genes such as NR4A and Thbs1. A high level of AMP accumulated in the apop...
ORGANISM(S): Mus musculus 
We performed Cleavage Under Targets and Release Using Nuclease (CUT&RUN) assays in BMDMs, deciphered MG53's binding site.
ORGANISM(S): Mus musculus 
To investigate the effects of the differences seen in the JUND binding patterns between LEW, WKY and WKY.LCrgn2 bone marrow derived macrophages (BMDMs), we have 1) analysed gene expression changes over a time course (4 time points: 0,2,4 and 8 hrs) of stimulation with lipopolysaccharide (LPS) using ...
ORGANISM(S): Rattus norvegicus 
Transcriptomics of BMSCs and BMDMs
Tissue macrophages from peritoneal cavity, lung, liver, spleen, small intestine and adipose tissue and M-CSF derived bone marrow derived macrophages (BMDMs) were determined for gene expression. Macrophages from six different tissues and BMDMs were compared for gene expression.
ORGANISM(S): Mus musculus 
Gene level expression estimate using the Whole Transcript (WT) Assay approach of the Gene 1.0 ST Array System for Mouse. This assay was done to identify the RIPK1-dependent gene expression changes in mouse BMDMs. Cost-effective gene-level analysis based on whole-transcript coverage. We analyzed Bone...
ORGANISM(S): Mus musculus 
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