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TranscriptomicsTranscription profiling of mouse follicular and marginal zone B-cells
Immature B cells in spleens of mouse and human differentiate into at least two subsets of mature B cells, the follicular (FO) B cells and the marginal zone (MZ) B cells, but functions, maturation and other properties of these cells are largely unknown. To solve these questions, in this study, we per...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-3599 | biostudies-arrayexpress
TranscriptomicsB-cell KO mice data
Using a systems biology approach, we discovered and dissected a three-way interaction between the immune system, the intestinal epithelium, and the microbiota. We found that mice lacking B lymphocytes, or lacking IgA, have low intestinal expression of lipid metabolism genes regulated by the transcri...
ORGANISM(S): Mus musculus 
2011-11-15 | E-GEOD-23573 | biostudies-arrayexpress
TranscriptomicsSplenic B cells from Hymenolepis diminuta-infected mice ameliorate colitis independent of T cells and via cooperation with macrophages
Mouse infection with the tapeworm Hymenolepis diminuta leads to a less severe DNBS-colitis. Increased Th2 and regulatory cytokine production in the spleen is a hallmark of Hymenolepis diminuta infection, therefore we hypothesized that given this microenvironment, splenic adaptive cells acquire an a...
ORGANISM(S): Mus musculus 
2015-02-20 | E-GEOD-61460 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Physcomitrella patens response to UV-B
comparison of gene expression between UV-B irradiated Physcomitrella patens gametophores with their non-irradiated controls in two different UV irradiation fields.
ORGANISM(S): Physcomitrella patens 
2010-04-28 | E-MEXP-2508 | biostudies-arrayexpress
TranscriptomicsInnate response activator B cells are sentinels that guard against polymicrobial sepsis
Innate immunity is fundamental to recognition and clearance of bacterial infection. The relevant cells and molecules that orchestrate an effective response, however, remain incompletely understood. Here we describe a previously unknown population of B cells, which we have named innate response activ...
ORGANISM(S): Mus musculus 
2012-02-07 | E-GEOD-32372 | biostudies-arrayexpress
TranscriptomicsGene expression analysis of Lamin B receptor deficient hematopoietic cells
Gene expression analysis of Lamin B receptor deficient hematopoietic cells
ORGANISM(S): Mus musculus 
2011-12-21 | E-TABM-1134 | biostudies-arrayexpress
TranscriptomicsCrosstalk between B lymphocytes, microbiota and the intestinal epithelium governs immunity versus metabolism in the gut
This SuperSeries is composed of the following subset Series: GSE23573: B-cell KO mice data GSE23933: human duodenum biopsy data GSE33884: The role of immunoglobulin A GSE33885: The role of transcription factor Gata4 Refer to individual Series
ORGANISM(S): Mus musculus 
2011-11-15 | E-GEOD-23934 | biostudies-arrayexpress
TranscriptomicsEffect of amphotericin B on Aspergillus fumigatus
Amphotericin B (AMB) is the most widely used polyene antifungal drug for the treatment of systemic fungal infections including invasive aspergillosis. We aimed to understand molecular targets of AMB in Aspergillus fumigatus (Afu) by genomic approaches. Amphotericin B (AMB) is the most widely used p...
ORGANISM(S): Aspergillus fumigatus 
2010-05-26 | E-GEOD-10505 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of chemokines and chemokine receptors on B-cells in chronically HIV-1 infected patients
From the analysis of all genes included in the array a number of individual genes were identified as dys-regulated in HIV-1 infected patients compared to healthy controls. In particular, increased CXCL13 expression in all individual patient samples. Abstract from publication: HIV-1 infection is ass...
ORGANISM(S): Homo sapiens 
2010-06-25 | E-GEOD-12597 | biostudies-arrayexpress
TranscriptomicsCytokimera GIL-11 rescued IL-6R deficient mice from partial hepatectomy-induced death by signaling via non-natural gp130:LIFR:IL-11R complexes
All except one cytokine of the Interleukin (IL-)6 family share glycoprotein (gp) 130 as the common b receptor chain. Whereas Interleukin (IL-)11 signal via the non-signaling IL-11 receptor (IL-11R) and gp130 homodimers, leukemia inhibitory factor (LIF) recruits gp130:LIF receptor (LIFR) heterodimers...
ORGANISM(S): Mus musculus 
2023-04-19 | GSE226064 | GEO
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