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TranscriptomicsMLLT10 gene recombinations in pediatric T-Acute Lymphoblastic Leukemia
MLLT10, a 24 exons gene at 10p12, is known in leukemogenesis as partner of MLL or PICALM and recently NAP1L1. We identified HNRNPH1 and DDX3X, genes involved in RNA processing, as new MLLT10 partners in 2 cases of pediatric NOTCH1 positive T-ALL. HNRNPH1/5q35 encodes for a member of the ubiquitously...
ORGANISM(S): Homo sapiens 
2013-07-03 | E-GEOD-42765 | biostudies-arrayexpress
UnknownCardiovascular disease and diagnosis of advanced prostate cancer.
Not available
S-EPMC12486819 | biostudies-literature
TranscriptomicsLinking genomic lesions with minimal residual disease improves prognostic stratification in children with T-cell acute lymphoblastic leukaemia
GEP class prediction in association with CI-FISH (42 candidate genes) and patient MRD stratification Combined Interphase FISH (CI-FISH) for 42 candidate genes and Single Nucleotide Polymorphism (SNP) arrays were applied in a series of 51 T-ALL patients enrolled in Italy into the AIEOP-BFM ALL2000 pr...
ORGANISM(S): Homo sapiens 
2013-11-05 | E-GEOD-39816 | biostudies-arrayexpress
TranscriptomicsGenotyping of human Infant ALL samples to detect MLL-cooperating aberrations
In this study we explored the genotype of Infant ALL to detect MLL-cooperating aberrations, hidden to conventional techniques. In order to limit further heterogeneity, we focused on patients carrying the t(4;11) translocation, the most frequent genetic abnormality in Infant ALL. Final aim was to get...
ORGANISM(S): Homo sapiens 
2009-12-03 | E-TABM-511 | biostudies-arrayexpress
UnknownNew Viscoelastic Hydrogel Hymovis MO.RE. Single Intra-articular Injection for the Treatment of Knee Osteoarthritis in Sportsmen: Safety and Efficacy Study Results.
Not available
S-EPMC8195240 | biostudies-literature
UnknownLCK over-expression drives STAT5 oncogenic signaling in PAX5 translocated BCP-ALL patients.
Not available
S-EPMC4359315 | biostudies-literature
UnknownIdentification of germline susceptibility loci in ETV6-RUNX1-rearranged childhood acute lymphoblastic leukemia.
Not available
S-EPMC3356560 | biostudies-literature
UnknownFunctional protein network activation mapping reveals new potential molecular drug targets for poor prognosis pediatric BCP-ALL.
Not available
S-EPMC2958847 | biostudies-literature
TranscriptomicsPAX5TEL GENE EXPRESSION IN PREBI CELLS - FAZIO G.
In the present study, we investigated PAX5TEL function in transcription processes by transduction of PAX5TEL construct in wild type preBI cells, a primary culture of immature B cells expressing endogenous wild type PAX5 protein.
ORGANISM(S): Mus musculus 
2012-11-13 | E-MEXP-3095 | biostudies-arrayexpress
UnknownHigh expression of miR-125b-2 and SNORD116 noncoding RNA clusters characterize ERG-related B cell precursor acute lymphoblastic leukemia.
Not available
S-EPMC5522075 | biostudies-literature
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