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ProteomicsEngineering Palmitoylated G-Quadruplex Aptamers to Target STAT3 and Overcome Therapeutic Resistance in Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies owing to extensive therapeutic resistance and limited treatment options. Increasing evidence indicates that activation of the IL-6–JAK–STAT3 pathway represents a major adaptive survival mechanism that promotes resistance ...
ORGANISM(S): Mus musculus (Mouse) 
2026-08-27 | PXD082487 | Pride
Aptamer  stat3  kras  g4 
TranscriptomicsComparison of vineyard, enological and laboratory yeast transcriptomes at different steps of the fermentation curve
Here we report the massively parallel cDNA sequencing (RNA-seq) analysis performed using high throughput sequencing of four vineyard yeast strains collected from the vineyards of the M-bM-^@M-^\Prosecco di Conegliano-ValdobbiadeneM-bM-^@M-^] (P283 and P301 strains) and Piave AO (Appellation of origi...
ORGANISM(S): Saccharomyces cerevisiae 
2014-03-31 | E-GEOD-44845 | biostudies-arrayexpress
UnknownThe contribution of the Middle Triassic fossil assemblage of Monte San Giorgio to insect evolution.
Not available
S-EPMC11336256 | biostudies-literature
ProteomicsEpigenetic Impairment of tumor potential of AML-derived extracellular vesicles
The biological active cargo of leukemia-derived extracellular vesicles (EVs) favours a wide variety of cancer-supportive mechanisms, including aberrant proliferative signalling, immune escape and drug resistance. However, whether and in which extent anti-neoplastic drugs affect EV cargo sorting is ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD042168 | Pride
Vesicle Leukemia Tumorigenicity Epigenetic Saha 
UnknownReduced mitochondrial Ca(2+) transients stimulate autophagy in human fibroblasts carrying the 13514A>G mutation of the ND5 subunit of NADH dehydrogenase.
Not available
S-EPMC4716301 | biostudies-literature
UnknownNovel LRPPRC compound heterozygous mutation in a child with early-onset Leigh syndrome French-Canadian type: case report of an Italian patient.
Not available
S-EPMC7517646 | biostudies-literature
UnknownRecalibration of the insect evolutionary time scale using Monte San Giorgio fossils suggests survival of key lineages through the End-Permian Extinction.
Not available
S-EPMC6790769 | biostudies-literature
UnknownPost-transcriptional control of KRAS: functional roles of 5'UTR RNA G-quadruplexes, long noncoding RNA, and hnRNPA1.
Not available
S-EPMC12449053 | biostudies-literature
UnknownExpanding the Mutational Spectrum of TSPEAR in Ectodermal Dysplasia Type 14: A Familial Case Study.
Not available
S-EPMC12111227 | biostudies-literature
TranscriptomicsPlatelet RNA-Seq
Platelet-rich plasma (PRP) has been obtained by centrifuging whole blood at 160 g for 15 min at room temperature. Platelets have been activated with 2 different physiologic agonists, namely collagen (60ug/mL) or Thrombin Receptor Activating Peptide (TRAP 25uM) under continuous stirring. An aliquot o...
ORGANISM(S): Homo sapiens 
2015-04-27 | E-MTAB-2355 | biostudies-arrayexpress
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