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In order to analyse the globus pallidus proteome in a large-scale format, we used a multi-dimensional fractionation approach which combines isolation of anatomically-defined nuclei, and protein/peptide chromatographic fractionation strategies coupled to mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2018-10-19 | PXD000757 | Pride
In order to analyse the globus pallidus proteome in a large-scale format, we used a multi-dimensional fractionation approach which combines isolation of anatomically-defined nuclei, and protein/peptide chromatographic fractionation strategies coupled to mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2018-10-19 | PXD000755 | Pride
Genome-wide transcriptome analysis of expression changes in Globus Pallidus interna (GPi) from Parkinson's disease brain tissue versus control brain tissue. Post-mortem brain expression analysis performed in 10 PD brain samples and 10 control brain samples.
ORGANISM(S): Homo sapiens 
Molecular basis of transition to addiction in vulnerable individuals is largely unknown. We hypothesized that human susceptibility genes can be identified on the basis of conserved molecular mechanisms in rodent brains. We used a short-term cocaine-dependent conditioned place preference (CPP) to ide...
ORGANISM(S): Mus musculus 
Molecular basis of transition to addiction in vulnerable individuals is largely unknown. We hypothesized that human susceptibility genes can be identified on the basis of conserved molecular mechanisms in rodent brains. We used a short-term cocaine-dependent conditioned place preference (CPP) to ide...
ORGANISM(S): Mus musculus 
This study examined global proteomic changes in postmortem globus pallidus (GP) tissue from Non-Hispanic Whites and African American individuals who were cognitively normal or had Alzheimer's disease using LC-MS3 on an Orbitrap Fusion Lumos. Proteins were quantified in the LC-MS3 experiments using T...
ORGANISM(S): Homo sapiens (Human) 
2020-10-19 | PXD014371 | Pride
Progressive supranuclear palsy (PSP) is a neurodegenerative disorder clinically characterized by progressive postural instability, supranuclear gaze palsy, parkinsonism, and cognitive decline caused by degeneration in specific areas of the brain including globus pallidus (GP), substantia nigra, and ...
ORGANISM(S): Homo sapiens (Human) 
2022-12-08 | PXD031648 | Pride
DNase-seq on 84 year old adult male human globus pallidal tissue For data usage terms and conditions, please refer to http://www.genome.gov/27528022 and http://www.genome.gov/Pages/Research/ENCODE/ENCODE_Data_Use_Policy_for_External_Users_03-07-14.pdf
ORGANISM(S): Homo sapiens 
2016-12-07 | GSE90395 | GEO
Cell type-specific oxidative stress genomic signatures in the globus pallidus of dopamine depleted mice
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