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ProteomicsSuperior metabolic improvement of polycystic ovary syndrome traits after GLP1-based multi-agonist therapy
Polycystic ovary syndrome (PCOS) is a heterogeneous condition, of polyhedric pathogenesis and clinical presentation, defined by oligo-/anovulation, hyperandrogenism and/or polycystic ovaries. Metabolic complications are highly common also in patients suffering PCOS, including obesity, insulin resist...
ORGANISM(S): Mus musculus (Mouse) 
2024-10-02 | PXD044134 | Pride
Pcos Glp1 Glp1/gip Glp1/gip/glucagon Glp1/e 
MetabolomicsMetabolomic and lipidomic profiles in response to exogenous insulin and GLP-1 infusions during prolonged fasting
Not available
ORGANISM(S): Mirounga angustirostris 
ST000107 | MetabolomicsWorkbench
MetabolomicsMetabolomic & lipidomic profiles in response to exogenous insulin & GLP-1 infusions during prolonged fasting (GCMS)
Not available
ORGANISM(S): Mirounga angustirostris 
ST000048 | MetabolomicsWorkbench
MetabolomicsActivation of ectopic olfactory receptor 544 induces GLP-1 secretion, alters gut microbiome, and improves intestinal permeability.
Not available
ORGANISM(S): Mus musculus 
ST001399 | MetabolomicsWorkbench
MetabolomicsWeight loss and weight maintenance obtained with or without GLP-1 analogue treatment decrease branched chain amino acid levels.
Not available
ORGANISM(S): Homo sapiens 
ST000502 | MetabolomicsWorkbench
GenomicsMaternal antagonism of Glp1 reverses the adverse outcomes of sleeve gastrectomy on mouse offspring
Maternal antagonism of Glp1 reverses the adverse outcomes of sleeve gastrectomy on mouse offspring
PRJNA802853 | ENA
TranscriptomicsMaternal antagonism of Glp1 reverses the adverse outcomes of sleeve gastrectomy on mouse offspring
Maternal sleeve gastrectomy in lean mice leads to small-for-gestational births and higher sensitivity of offspring to a high fat diet. These effects are reduced by maternal treatment with a Glp1 antagonist.
ORGANISM(S): Mus musculus 
2022-04-01 | GSE195998 | GEO
UnknownChronic GLP1 therapy reduces postprandial IL6 in obese humans with prediabetes.
Not available
S-EPMC10769508 | biostudies-literature
UnknownGLP1 Exerts Paracrine Activity in the Intestinal Lumen of Human Colon.
Not available
S-EPMC8998470 | biostudies-literature
UnknownSuperior metabolic improvement of polycystic ovary syndrome traits after GLP1-based multi-agonist therapy.
Not available
S-EPMC11445520 | biostudies-literature
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