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ProteomicsLC-MS/MS analysis of GLUT4-associated proteins in mouse lateral septum tissue after social novelty preference
This dataset contains raw mass spectrometry files from mouse lateral septum samples collected after the social novelty preference test. Lateral septum tissues were incubated with synthetic GLUT4 WT or GLUT4 2A peptides, followed by GLUT4 immunoprecipitation and LC-MS/MS analysis. The experiment was ...
ORGANISM(S): Mus musculus (Mouse) 
2026-08-20 | PXD079796 | Pride
Mouse brain social 
ProteomicsThe intracellular helical bundle of human glucose transporter GLUT4 is of importance for complex formation with ASPL
DSS-based cross-linking MS of the human glucose transporter GLUT4 in interaction with the human TUG homolog Alveolar Soft Part Sarcoma Locus (ASPL) protein.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-03-27 | MSV000091556 | MassIVE
TranscriptomicsZinc Finger Protein 407 (ZFP407) Regulates Insulin-Stimulated Glucose Uptake and Glucose Transporter 4 (Glut4) mRNA
Using RNA-Seq, we compared the transcriptomes of differentiated 3T3-L1 adipocytes for control and ZFP407-deficient cells Differentiated 3T3-L1 cells were electroporated with control or 1 of 2 Zfp407 siRNAs. Six independent siRNA electroporations were conducted for the control siRNA and 3 independent...
ORGANISM(S): Mus musculus 
2015-01-16 | E-GEOD-64757 | biostudies-arrayexpress
ProteomicsIdentifying a GSK3-TRARG1 signaling axis reveals BCL9L as a novel regulator of GLUT4 trafficking
The trafficking regulator of GLUT4-1 (TRARG1) protein positively regulates insulin-stimulated GLUT4 trafficking. Here we identify post-translational modifications on TRARG1 and identify that GSK3 is the upstream kinase responsible for TRARG1 phosphorylation at Serines 72, 76, and 80. We employ affin...
ORGANISM(S): Mus musculus (Mouse) 
2022-08-12 | PXD022765 | Pride
Bcl9l Glut4 Trarg1 Trafficking Phosphorylation 
TranscriptomicsAdipose Rab10 Knockout Causes Insulin Resistance through Impaired Glucose Uptake
Insulin action in adipocytes affects whole-body insulin sensitivity. Studies of adipose-specific Glut4 knockout mice have established that adipose Glut4 contributes to the control of systemic glucose homeostasis. Presumably, this reflects a role for Glut4-mediated glucose transport in the regulation...
ORGANISM(S): Mus musculus 
2016-06-30 | E-GEOD-70123 | biostudies-arrayexpress
Transcriptomicsadipose tissue Glut4 overexpression or knockout
The goal of this study is to determine the effects of adipose-specific Glut4 overexpression or knockout on changes in adipose tissue global gene expression Three mice from each of four genotypes were studied using a total of 12 microarray chips: aP2-Cre transgenic mice (controls for adipose-Glut4-/-...
ORGANISM(S): Mus musculus 
2012-01-28 | E-GEOD-35378 | biostudies-arrayexpress
Transcriptomicsadipose tissue Glut4 overexpression or knockout
The goal of this study is to determine the effects of adipose-specific Glut4 overexpression or knockout on changes in adipose tissue global gene expression
ORGANISM(S): Mus musculus 
2012-01-28 | GSE35378 | GEO
Genomics
Sequencing data for GLUT4
PRJNA1139656 | ENA
ProteomicsTankyrase modulates insulin sensitivity in skeletal muscle cells by regulating stability of GLUT4 vesicle proteins
Tankyrase1 and 2, members of the poly(ADP-ribose) polymerase family, play a role in multiple biological processes including Wnt signalling and glucose uptake. However, their role in glucose uptake remains elusive, particularly in skeletal muscle cells. Treatment of differentiated L6 myotubes with th...
ORGANISM(S): Rattus norvegicus (Rat) 
2018-04-17 | PXD007182 | Pride
Gsv Tankyrase Skeletal muscle 
TranscriptomicsExpression data from GLUT4 overexpression in FaDu head and neck cancer cell line
We demonstrate that GLUT4 up-regulation significantly increased cell migration and invasion in lower magligance head and neck cancer cell lines in vitro. We used microarrays to analyze the GLUT4 regulated gene expression underlying invasion-metastasis cascade.
ORGANISM(S): Homo sapiens 
2017-03-01 | GSE89631 | GEO
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