Gm1 - OmicsDI

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Genomics (772)
Transcriptomics (640)
Unknown (564)
Proteomics (38)
Metabolomics (16)
Other (3)
Clinical (1)

Organisms

Homo sapiens (348)
Mus musculus (316)
Caenorhabditis elegans (305)
Drosophila melanogaster (131)
Saccharomyces cerevisiae (57)
Schizosaccharomyces pombe (36)
Arabidopsis thaliana (32)
Rattus norvegicus (22)
Escherichia coli str. K-12 substr. MG1655 (17)
Escherichia coli (11)
Schizosaccharomyces pombe 972h- (5)
Danio rerio (5)
Tetrahymena thermophila (4)
Saccharomyces cerevisiae S288C (4)
Salmonella enterica subsp. enterica serovar Typhimurium (4)
Escherichia coli K-12 (4)
Papio anubis (3)
Zea mays (3)
Canis lupus familiaris (3)
Pseudomonas aeruginosa (3)
Aplysia californica (2)
Micropterus salmoides (2)
Bombyx mori (2)
Xenopus tropicalis (2)
Trypanosoma cruzi (2)
Yersinia pestis (2)
Bacillus subtilis (2)
Staphylococcus aureus (2)
Streptococcus pneumoniae (2)
Solanum lycopersicum (2)

Organisms

Mus musculus (6)
Homo sapiens (4)
fungus metagenome (2)
Beduini massiliensis (1)
Xanthomonas hortorum pv. pelargonii (1)
Ceratocystis manginecans (1)
bacterium GM1(2013) (1)
Campylobacter jejuni subsp. jejuni HB93-13 (1)
Campylobacter jejuni subsp. jejuni 260.94 (1)
Bacillus sp. GM1 (1)
cave metagenome (1)
Oryza sativa (1)
Gallus gallus (1)

Repository

biostudies-arrayexpress (1382)
ENA (28)
MassIVE (12)
MetabolomicsWorkbench (10)
pride (9)
PeptideAtlas (8)
geo (5)
jPOST (5)
MetaboLights (4)
GNPS (2)
GPMDB (2)
EGA (1)
PAXDB (1)

Tissue

Muscle (3)
Blood (3)
Brain (2)
Liver (2)
Cell culture (2)
Ventricles (1)
Epididymal fat (1)
B-cells (1)
Adipose tissue (1)
Heart (1)
Macrophages (1)
Eye tissue (1)
Cultured cells (1)
Blood plasma (1)
Brain (1)
Glutamatergic neuron (1)
Mammary gland (1)

Disease

Normal (7)
Breast cancer (2)
Not Available (2)
Eye disease (2)
Respiratory syncytial virus infection (1)
Mild hyperglycemia, liver dysfunction, and renal glycosuria (1)
Primary tumor (1)
Cancer (1)
Breast carcinoma (1)
Colorectal Neoplasms (1)
COPD (1)
Obesity (1)
Malaria (1)
Cancer (1)
Alzheimer's disease (1)
GM1 gangliosidosis (1)
Tay-Sachs disease (1)
Urinary tract infection (1)

Technology Type

Mass Spectrometry (19)
ESI (10)
Shotgun proteomics (6)
Mass spectrometry (3)
NMR spectroscopy (1)
EI (1)
Bottom-up proteomics (1)
Data-dependent acquisition (1)
Gel-based experiment (1)
Mass spectrometry imaging (1)

Instrument Platform

NextSeq 500 (41)
Illumina HiSeq 2000 (38)
Illumina NovaSeq 6000 (27)
Illumina HiSeq 4000 (24)
Illumina HiSeq 2500 (23)
NextSeq 2000 (7)
Illumina MiSeq (6)
NextSeq 550 (6)
Illumina HiSeq 3000 (6)
Illumina Genome Analyzer IIx (5)
AB SOLiD 4 System (4)
Illumina Genome Analyzer II (3)
AB 5500 Genetic Analyzer (2)
GenePix 4000B [Axon Instruments] (2)
NextSeq 1000 (2)
BGISEQ-500 (2)
Illumina HiSeq 1500 (2)
Shanghai Genefund Biotech Co., Ltd Illumina NovaSeq 6000 (1)
Solexa 2G Genome Analyzer (1)
Tapestation (1)
Helicos (1)
IPstar-compact (diagenode) (1)
Covaris E220evolution (1)
G2565AA DNA microarray scanner [Agilent] (1)
Axon- GenePix4000B (1)
ScanArray Express HT [PerkinElmer] (1)
Scanning hardware (1)
Ion Torrent PGM (1)
DNBSEQ-G400 (1)
Illumina HiSeq 1000 (1)

Publication Date

2013 (332)
2014 (169)
2015 (163)
2010 (152)
2012 (120)
2011 (106)
2016 (103)
2021 (30)
2009 (28)
2008 (27)
2023 (26)
2018 (25)
2025 (24)
2019 (21)
2022 (20)
2020 (20)
2017 (13)
2026 (12)
2024 (12)
2007 (11)
2006 (4)
2005 (2)

UNIPROT ID/AC

6PGL_HELPY (1)
85962.C694_00040 (1)
85962.C694_00275 (1)
85962.C694_00510 (1)
85962.C694_00935 (1)
85962.C694_01080 (1)
85962.C694_01205 (1)
85962.C694_02750 (1)
85962.C694_03200 (1)
85962.C694_03205 (1)
85962.C694_03530 (1)
85962.C694_03705 (1)
85962.C694_03715 (1)
85962.C694_03730 (1)
85962.C694_04635 (1)
85962.C694_04640 (1)
85962.C694_05100 (1)
85962.C694_05145 (1)
85962.C694_05150 (1)
85962.C694_05210 (1)
85962.C694_05650 (1)
85962.C694_05655 (1)
85962.C694_05750 (1)
85962.C694_05755 (1)
85962.C694_06925 (1)
85962.C694_06985 (1)
85962.C694_07065 (1)
85962.C694_07285 (1)
85962.C694_07295 (1)
85962.C694_07300 (1)

CHEBI ID

CHEBI:134574 (2)
CHEBI:137836 (2)
CHEBI:134572 (2)
CHEBI:72529 (2)
CHEBI:72534 (2)
CHEBI:72528 (2)
CHEBI:72523 (2)
CHEBI:72519 (2)
CHEBI:72518 (2)
CHEBI:85870 (2)
CHEBI:85694 (2)
CHEBI:85842 (2)
CHEBI:85742 (2)
CHEBI:85743 (2)
CHEBI:84660 (2)
CHEBI:84661 (2)
CHEBI:85736 (2)
CHEBI:90302 (2)
CHEBI:84662 (2)
CHEBI:84665 (2)
CHEBI:85874 (2)
CHEBI:85726 (2)
CHEBI:72514 (2)
CHEBI:85749 (2)
CHEBI:85750 (2)
CHEBI:85876 (2)
CHEBI:85741 (2)
CHEBI:64566 (2)
CHEBI:64561 (2)
CHEBI:64568 (2)

Metabolite Name

PS(O-42:7) PS(P-42:6) (1)
PS(O-42:6/P-42:5)d (1)
PS(O-42:6/P-42:5)b (1)
PS(O-42:6/P-42:5)a (1)
PS(O-42:5/P-42:4) (1)
PS(O-42:3/P-42:2) (1)
PS(O-42:2) PS(P-42:1) (1)
PS(O-40:6/P-40:5)c (1)
PS(O-40:6) PS(P-40:5)b (1)
PS(O-40:6) PS(P-40:5)a (1)
PS(O-40:5/P-40:4)c (1)
PS(O-40:5/P-40:4)b (1)
PS(O-40:5) PS(P-40:4)a (1)
PS(O-40:4/P-40:3) (1)
PS(O-40:3) PS(P-40:2) (1)
PS(O-40:2/P-40:1) (1)
PS(O-40:0) (1)
PS(O-38:6) PS(P-38:5) (1)
PS(O-38:5) PS(P-38:4) (1)
PS(O-38:4/P-38:3) (1)
PS(O-38:3/P-38:2) (1)
PS(O-38:2) PS(P-38:1) (1)
PS(O-38:1) PS(P-38:0) (1)
PS(O-36:3/P-36:2)a (1)
PS(O-34:0) (1)
PS(44:8)b (1)
PS(44:6) (1)
PS(44:5)b (1)
PS(44:5)a (1)
PS(44:4)b (1)

First Public Date

2024 (4)
2023 (4)
2022 (3)
2020 (3)
2019 (3)
2026 (2)
2025 (2)
2018 (2)
2015 (2)
2013 (2)
2014 (1)

Classification

bacteria (2)

Study status

Completed (1)

Study type

ChIP-seq (721)
ChIP-chip by tiling array (221)
Transcription profiling by array (103)
RNA-seq of coding RNA (88)
ChIP-chip by array (77)
Other (35)
Methylation profiling by array (33)
Methylation profiling by high throughput sequencing (21)
Cell line - High-throughput sequencing (11)
Unknown experiment type (9)
CLIP-seq (8)
RIP-seq (8)
High-throughput sequencing (6)
Comparative genomic hybridization by array (6)
RNA-seq of non coding RNA (6)
CUT&RUN (5)
RIP-chip by array (4)
Proteomic profiling by array (3)
MeDIP-seq (2)
Animal - High-throughput sequencing (2)
Transcription profiling by tiling array (2)
Hi-C (2)
Two-color microarray (1)
MicroRNA profiling by high-throughput sequencing (1)
CLIP-Seq (1)
Human - High-throughput sequencing (1)
RNAi profiling by array (1)
MBD-seq (1)
DNA-seq (1)
RNA-seq of coding RNA from single cells (1)

Release Date

2013 (357)
2014 (194)
2015 (193)
2010 (167)
2012 (138)
2016 (133)
2011 (123)
2021 (73)
2020 (73)
2022 (72)
2023 (65)
2018 (57)
2019 (49)
2025 (46)
2008 (39)
2009 (37)
2024 (34)
2017 (34)
2007 (17)
2026 (15)
2006 (6)
2005 (6)
2003 (3)
2002 (3)
2001 (3)
2004 (2)
1999 (2)
1998 (2)
2000 (1)
1992 (1)

Lab affiliation

Cambridge Institute for Medical Research, University of Cambridge (1)
Center for Mass Spectrometry and Optical Spectroscopy (CeMOS), Mannheim University of Applied Sciences, Paul-Wittsack Str. 10, 68163, Mannheim, Germany. Mannheim Center for Translational Neuroscience (MCTN), Medical Faculty Mannheim, Heidelberg University, 69120 Heidelberg, Germany. Medical Faculty, Heidelberg University, 69120 Heidelberg, Germany. (1)
Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II (1)
Department of Pharmacology, Penn State College of Medicine (1)
Institute of the Science of Food Production (ISPA) – National Research Council, Largo Braccini 2, 10095 Grugliasco, TO, Italy (1)
Member, St. Jude Faculty Jewelers For Children Endowed Chair in Genetics and Gene Therapy (1)
Molecular and Cell Biology University of California, Berkeley (1)
Oncology Pathology, Karolinska Institutet, and Scilifelab, Stockholm, Sweden (1)
PAPPSO,MICALIS,INRA, France (1)

Location

China (1)

Keyword

Capecitabine (1)
Leucovorin (1)
Fluorouracil (1)

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Altered GM1 catabolism affects NMDAR-mediated Ca2+ signaling at ER-PM junctions and increases synaptic spine formation

GM1-ganglioside, an abundant GSL in neuronal membranes, is integral to ER-PM junctions where it interacts with synaptic proteins/receptors and regulates Ca2+ signaling.

ORGANISM(S): Mus musculus (Mouse)

2024-03-19 | PXD042994 | Pride

Bacillus sp. GM1

Bacillus sp. GM1 Genome sequencing

PRJNA1173939 | ENA

SialidaseNeu3action on GM1 ganglioside is neuroprotective in GM1 Gangliosidosis

PRJNA1010227 | ENA

bacterium GM1(2013)

bacterium GM1(2013) Genome sequencing

PRJNA230873 | ENA

GM1 promotes early Aβ oligomer formation and maintenance

The aggregation of amyloid beta (Aβ) peptide is associated with Alzheimer’s disease (AD) pathogenesis. Cell membrane composition, especially monosialotetrahexosylganglioside (GM1), is known to promote the formation of Aβ fibrils, yet little is known about the roles of GM1 in the early steps of Aβ ol...

ORGANISM(S): Homo sapiens (Human)

2023-05-10 | PXD029117 | Pride

Oligomers Gm1 Alzheimer's disease Amyloid beta

SialidaseNeu3action on GM1 ganglioside is neuroprotective in GM1 Gangliosidosis

GM1 gangliosidosis is a neurodegenerative disorder caused by mutations in theGLB1gene, which encodes lysosomalb-galactosidase. The enzyme deficiency blocks GM1 ganglioside catabolism, leading to accumulation of GM1 ganglioside and asialo-GM1 ganglioside (GA1 glycolipid) in brain. This disease can pr...

ORGANISM(S): Mus musculus

2023-12-14 | GSE241844 | GEO

Xanthomonas hortorum pv. pelargonii strain:GM1

Xanthomonas hortorum pv. pelargonii strain:GM1 Genome sequencing

PRJNA505722 | ENA

Burden of caregiving of individuals with GM1 and GM2 gangliosidoses in the United States: a qualitative study.

Not available

S-EPMC12632087 | biostudies-literature

Ceratocystis manginecans isolate:GM1

Ceratocystis manginecans isolate:GM1 Genome sequencing

PRJNA922234 | ENA

Sialidase NEU3 action on GM1 ganglioside is neuroprotective in GM1 gangliosidosis.

Not available

S-EPMC10694597 | biostudies-literature

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