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TranscriptomicsWhole-transcriptome of the liver in 15-day-old C3H/HeOuJ and CAST/EiJ mice.
Male C3H/HeOuJ and CAST/EiJ mice were treated with diethylnitrosamine to induce liver tumours. We collected liver samples from untreated P15 mice for control experiments. Liver tissue samples were snap frozen in liquid nitrogen and total RNA was extracted using the AllPrep 96 DNA/RNA Kit (Qiagen) ac...
ORGANISM(S): Mus musculus 
2020-06-18 | E-MTAB-8518 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiles of C3H/HeJ mouse liver tumours
Male C3H/HeOuJ mice are susceptible to spontaneous liver neoplasms. We aged a cohort of mice for up to 76 weeks and isolated liver tumours. Tumours were bisected: one half was snap frozen in liquid nitrogen for RNA extraction and the other half of the tumour was processed for histological examinatio...
ORGANISM(S): Mus musculus 
2018-07-29 | E-MTAB-6971 | biostudies-arrayexpress
TranscriptomicsMolecular profiling of Ctcf hemizygous mouse embryonic fibroblasts: RNA-seq
CTCF is a highly conserved and ubiquitously expressed protein involved in several fundamental processes such as fine-tuning gene expression, imprinting, X-chromosome inactivation and 3D chromatin organisation. To understand the impact of differences in the concentration of CTCF abundance on these pr...
ORGANISM(S): Mus musculus 
2018-07-29 | E-MTAB-6259 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E. coli high-cell-density recombinant and wild-type
The transcriptome profiles for wild-type (plasmid-free) and recombinant (plasmid-bearing) Escherichia coli during well-controlled synchronized high-cell-density fed-batch cultures were analyzed by DNA microarrays. It was observed that the growth phase significantly affected the transcriptome profile...
ORGANISM(S): Escherichia coli 
2009-08-25 | E-GEOD-17505 | biostudies-arrayexpress
MetabolomicsLaser-assisted rapid evaporative ionisation mass spectrometry (LA-REIMS) as a metabolomics platform in cervical cancer screening

BACKGROUND: The introduction of high-risk human papillomavirus (hrHPV) testing as part of primary cervical screening is anticipated to improve sensitivity, but also the number of women who will screen positive. Reflex cytology is the preferred triage test in most settings but ha...

2022-02-15 | MTBLS1371 | MetaboLights
UnknownCohesive Neighborhoods Where Social Expectations Are Shared May Have Positive Impact On Adolescent Mental Health.
Not available
S-EPMC5452616 | biostudies-literature
TranscriptomicsTranscription profiling of recombinant E. coli to heat-shock and dual heat-shock recombinant protein induction
Recombinant Escherichia coli cultures are used to manufacture numerous therapeutic proteins and industrial enzymes, where many of these processes use elevated temperatures to induce recombinant protein production. The heat-shock response in wild-type E. coli has been well studied. In this study, t...
ORGANISM(S): Escherichia coli 
2009-08-25 | E-GEOD-17507 | biostudies-arrayexpress
ProteomicsProteome and secretome of HepaRG cells
Primary human hepatocytes, the gold standard for in vitro studies of liver-related functions, suffer from uncertain availability and high variability in cell activity. Over years, a number of alternative hepatic cell lines have lost major liver-like functions, but not HepaRG cells. Therefore, their ...
ORGANISM(S): Homo sapiens (Human) 
2019-02-27 | PXD010304 | Pride
Copy numbers Hpr116 Proteome Functional assays Secretome Surrogate cell system to phh 
TranscriptomicsTranscription profiling of E. coli MG1655 treated with serine hydroxamate
For over 30 years, serine hydroxamate has been used to chemically stimulate a stringent response in Escherichia coli and other bacteria. These studies have elucidated numerous characteristics of the classical stringent response beyond the simple cellular response to an amino acid shortage, including...
ORGANISM(S): Escherichia coli 
2009-08-25 | E-GEOD-17506 | biostudies-arrayexpress
UnknownMeta-analysis of genome-wide DNA methylation and integrative omics of age in human skeletal muscle.
Not available
S-EPMC8350206 | biostudies-literature
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