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ProteomicsSART3 promotes homologous recombination repair by stimulating DNA–RNA hybrids removal and DNA end resection
DNA–RNA hybrids triggered by double-strand breaks (DSBs) are crucial intermediates during DSB repair, and their timely resolution requires numbers of RNA helicases, including DEAD box 1 (DDX1). However, how these helicases are recruited to DSB-induced hybrids in time remains largely unclear. Here, w...
ORGANISM(S): Homo sapiens (Human) 
2025-01-30 | PXD053595 | Pride
Sart3 Homologous recombination repair Dna–rna hybrids 
ProteomicsProteomic profiling of RAD52 interactome upon CPSF6 knockdown
Proteomic profiling of the RAD52 interactome was performed by immunoprecipitation followed by mass spectrometry (IP-MS). RAD52-Flag was immunoprecipitated from HEK293T cells upon depletion of CPSF6 (with shCPSF6) or under control conditions (shNC). The co-precipitated proteins were then identified b...
ORGANISM(S): Homo sapiens (Human) 
2026-10-27 | PXD070757 | Pride
Human Ip Rad52 Lc-ms/ms 
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