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TranscriptomicsTranscriptomic profiling of rhesus macaques vaccinated with ALVAC-SIV/gp120 adjuvanted in Alum or MF59.
The Canarypox/gp120/Alum vaccines decreased the risk of HIV acquisition in humans. We demonstrate here the efficacy of this vaccine regimen also in the SIVmac251 macaque model when we used the alum but not the MF59 adjuvant. Analysis of innate and adaptive cell responses, envelope antibodies Fc prof...
ORGANISM(S): Macaca mulatta 
2016-05-29 | E-GEOD-72624 | biostudies-arrayexpress
ProteomicsChinese Hamster Ovary cell proteins co-purified with recombinant HIV-1 envelopes, part 2
Chinese Hamster Ovary (CHO) cells are frequently used to produce recombinant HIV envelope protein gp120. In this study, we characterized the CHO proteins that become co-purified with gp120 when lectin affinity chromatography is used. Many of co-purified CHO proteins identified were extracellular m...
ORGANISM(S): Cricetulus Griseus (ncbitaxon:10029) 
2018-01-25 | MSV000081975 | MassIVE
ProteomicsChinese Hamster Ovary cell proteins co-purified with recombinant HIV-1 envelopes, part 1
Chinese Hamster Ovary (CHO) cells are frequently used to produce recombinant HIV envelope protein gp120. In this study, we characterized the CHO proteins that become co-purified with gp120 when lectin affinity chromatography is used. Many of co-purified CHO proteins identified were extracellular m...
ORGANISM(S): Cricetulus Griseus (ncbitaxon:10029) 
2018-01-25 | MSV000081974 | MassIVE
ProteomicsChinese Hamster Ovary cell proteins co-purified with recombinant HIV-1 envelopes, part 3
Chinese Hamster Ovary (CHO) cells are frequently used to produce recombinant HIV envelope protein gp120. In this study, we characterized the CHO proteins that become co-purified with gp120 when lectin affinity chromatography is used. Many of co-purified CHO proteins identified were extracellular m...
ORGANISM(S): Cricetulus Griseus (ncbitaxon:10029) 
2018-02-14 | MSV000082065 | MassIVE
ProteomicsChinese Hamster Ovary cell proteins co-purified with recombinant HIV-1 envelopes, part 4
Chinese Hamster Ovary (CHO) cells are frequently used to produce recombinant HIV envelope protein gp120. In this study, we characterized the CHO proteins that become co-purified with gp120 when lectin affinity chromatography is used. Many of co-purified CHO proteins identified were extracellular m...
ORGANISM(S): Cricetulus Griseus (ncbitaxon:10029) 
2018-01-25 | MSV000081976 | MassIVE
TranscriptomicsHIV-1 gp120 impairs B cell proliferation by inducing TGF-β1 production and FcRL4 expression via an α4β7-dependent mechanism
The anti-HIV humoral immune response following acute infection is delayed and ineffective. HIV envelope protein gp120 binds to and signals through α4β7 on T cells. We show that gp120 also binds and signals through α4β7 on B cells, resulting in an abortive proliferative response. In primary B cells, ...
ORGANISM(S): Homo sapiens 
2013-10-17 | E-GEOD-49019 | biostudies-arrayexpress
ProteomicsGP120 Mass Spectrometry Data to Analyse N-Glycosylation
Analysis of gp120 N-glycosylation. N-linked glycosylation sites of gp120 were interrogated for the presence of 55 glycoforms from chronic vs acute HIV virions.
ORGANISM(S): Human immunodeficiency virus 1 
2026-04-13 | PXD067311 | Pride
Glycosylation Hiv Gp120 
GenomicsTranscriptomic profiling of rhesus macaques vaccinated with Ad26/ALVAC+gp120 or DNA/ALVAC+gp120
Transcriptomic profiling of rhesus macaques vaccinated with Ad26/ALVAC+gp120 or DNA/ALVAC+gp120
PRJNA422217 | ENA
TranscriptomicsTranscription profiling of human CD4+ T cells induced by HIV-1 gp120/V3 loop peptides, time series
Comparative changes of gene expression in human primary CD4+ T cells induced by HIV-1 gp120/V3 loop synthetic peptides, during antigen presentation
ORGANISM(S): Homo sapiens 
2008-09-01 | E-MEXP-1586 | biostudies-arrayexpress
TranscriptomicsHIV gp120 modulates the vaginal transcriptome
During sexual transmission of HIV-1 from male to female partners, the vagina is the initial site of contact with HIV infected semen. The mechanism of HIV traversing the CD4 negative multi-layered stratified squamous epithelial barrier of the vagina to infect sub-epithelial susceptible immune cells, ...
ORGANISM(S): Homo sapiens 
2014-03-01 | E-GEOD-44914 | biostudies-arrayexpress
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