Sort   by:  
 Page size 
ProteomicsInvestigation of GPCR-G protein coupling by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) : the GPBAR1 case.
G protein-coupled receptors (GPCRs) are key classes of proteins for drug discovery research as many of them are still orphans and their function poorly known. Their activation mechanism is roughly divided in two states : active and unactive states however related dynamics to switch from one state to...
ORGANISM(S): Homo sapiens (Human) 
2025-09-08 | PXD047827 | Pride
Cryo-em Gpbar1 G protein Gpcr-g protein Tgr5 Hdx-ms Gpcr 
ProteomicsInvestigation of GPCR-G protein coupling by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) : the GPBAR1 case.
G protein-coupled receptors (GPCRs) are key classes of proteins for drug discovery research as many of them are still orphans and their function poorly known. Their activation mechanism is roughly divided in two states : active and unactive states however related dynamics to switch from one state to...
ORGANISM(S): Homo sapiens (Human) 
2026-06-12 | PXD047831 | Pride
Cryo-em Gpbar1 G protein Gpcr-g protein Tgr5 Hdx-ms Gpcr 
ProteomicsInvestigation of GPCR-G protein coupling by Hydrogen-Deuterium Exchange Mass Spectrometry (HDX-MS) : the GPBAR1 case.
G protein-coupled receptors (GPCRs) are key classes of proteins for drug discovery research as many of them are still orphans and their function poorly known. Their activation mechanism is roughly divided in two states : active and unactive states however related dynamics to switch from one state to...
ORGANISM(S): Homo sapiens (Human) 
2026-06-12 | PXD047822 | Pride
Cryo-em Gpbar1 G protein Gpcr-g protein Tgr5 Hdx-ms Gpcr 
GenomicsHigh fidelity detection of endogenous GPCR-G protein activity with a versatile mouse biosensor platform
High fidelity detection of endogenous GPCR-G protein activity with a versatile mouse biosensor platform
PRJNA1208098 | ENA
ModelsCroft2013 - GPCR-RGS interaction that compartmentalizes RGS activity
Croft2013 - GPCR-RGS interaction that compartmentalizes RGS activity Through modelling studies, the classic quaternary complex (ligand-GPCR-G-RGS) has been extended to include an additional layer of regulation through GPCR-RGS interactions, which facilitate the compartmentalization...
2024-09-02 | BIOMD0000000479 | BioModels
ModelsGPCR Cubic Ternary Complex with G protein Cycle, Redfern-Nichols 2023
A model of G protein activation using ordinary differential equations. Used to fit to experimental data obtained from the TRUPATH platform.
2025-05-22 | MODEL2306220001 | BioModels
UnknownStructural Aspects of GPCR-G Protein Coupling.
Not available
S-EPMC3877993 | biostudies-literature
UnknownRecent advances in computational studies of GPCR-G protein interactions.
Not available
S-EPMC6986689 | biostudies-literature
TranscriptomicsHigh fidelity detection of endogenous GPCR-G protein activity with a versatile mouse biosensor platform
Activation of heterotrimeric G-proteins (Gαβγ) by G-protein-coupled receptors (GPCRs) is a quintessential mechanism of transmembrane signal transduction in eukaryotes with major biomedical implications in therapeutic targeting. We developed a suite of publicly-accessible transgenic mouse lines that,...
ORGANISM(S): Mus musculus 
2026-01-08 | GSE286196 | GEO
UnknownAssembly of a GPCR-G Protein Complex.
Not available
S-EPMC6763313 | biostudies-literature
Sort   by:  
 Page size