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ProteomicsAgonist-induced phosphorylation of orthologues of the orphan receptor GPR35 as an activation biomarker
Mass spectrometry, mutagenesis and labelling with [32P] orthophosphate identified that each of the five hydroxy-amino acids in the intracellular C-terminal tail of human GPR35a became phosphorylated in response to agonist occupancy of the receptor and that, apart from Ser294, each of these contribut...
ORGANISM(S): Homo sapiens (Human) 
2022-04-04 | PXD030548 | Pride
Gpcr 
GenomicsGPR35 regulates anxiety susceptibility
GPR35 regulates colitis-associated anxiety susceptibility
PRJEB84375 | ENA
ProteomicsGPR35 promotes glycolysis, proliferation and oncogenic signalling by engaging with the sodium potassium pump
We used human embryonic kidney HEK293T cells transfected with human GPR35 cDNAs as baits that were engineered to express Strep or hemagglutinin (HA) tags at the C terminus to perform an unbiased proteomics survey for GPR35 interaction partners.
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD011269 | Pride
Gpr35  na/k atpase 
GenomicsGPR35-long drives gastrointestinal tumor growth
Overexpression and enhanced signaling activity of the epithelial GPR35 isoform drives gastrointestinal tumorigenesis
PRJEB101778 | ENA
GenomicsGPR35 enhance mast cell mediator secretion
GPR35-positive mast cells are enriched in primary sclerosing cholangitis and show an enhanced secretory phenotype
PRJEB108218 | ENA
GenomicsGPR35+ tumor-associated neutrophils promote tumor growth in hepatocellular carcinoma.
GPR35+ tumor-associated neutrophils promote tumor growth in hepatocellular carcinoma.
PRJNA1305477 | ENA
GenomicsInfluence of GPR35 deficiency on the ileal and macrophage transcriptome
Influence of GPR35 deficiency on the ileal and macrophage transcriptome
PRJNA1063257 | ENA
GenomicsLow input RNA sequencing of GPR35-positive and negative intestinal macrophages
Low input RNA sequencing of GPR35-positive and negative intestinal macrophages
PRJNA545130 | ENA
TranscriptomicsGPR35+ tumor-associated neutrophils promote tumor growth in hepatocellular carcinoma.
Bulk RNA-seq profiling of tumor-associated neutrophils from Hepa1-6 mouse hepatocellular carcinoma (HCC) models. Neutrophils were isolated from mice HCC tissues and classified as GPR35+ or GPR35- subsets (n=3 per group). Differential expression analysis revealed significant upregulation of MAPK sign...
ORGANISM(S): Mus musculus 
2026-04-05 | GSE305407 | GEO
TranscriptomicsLow input RNA sequencing of GPR35-positive and negative intestinal macrophages
Aim: We aimed to determine differences in transcriptional profiles of GPR35-positive and negative macrophages in the steady state intestine. Method: Corresponding subpopulations were sorted by FACS from intestinal lamina propria cells of unmanipulated wild-type C56BL/6 mice. RNA from 4 replicates of...
ORGANISM(S): Mus musculus 
2020-06-25 | GSE131858 | GEO
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