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ProteomicsRetinal Pathological Features and Proteome Signatures of Alzheimer’s Disease
Alzheimer’s disease (AD) pathologies were discovered in the easily accessible neurosensory retina. Yet, their specific nature, topographical distribution, and relationship with disease status remain undefined. Here, we histologically determined burden and spatial distribution of amyloid β-protein (A...
ORGANISM(S): Homo sapiens (Human) 
2025-10-22 | PXD040225 | Pride
Proteomics Brain Alzheimer's disease Retina 
ProteomicsH3K9me3 epigenetic derepression reverses Alzheimer’s-like pathology and improves cognition via immunomodulation and Vgf network activation
Alzheimer's disease (AD) is associated with excessive epigenome histone 3 lysine 9 trimethylation (H3K9me3), repressing genes involved in synaptic plasticity and memory. In this study, we explored the therapeutic potential of ETP69, an inhibitor of the H3K9me3 methyltransferase SUV39H1, in both old ...
ORGANISM(S): Mus musculus (Mouse) 
2026-10-26 | PXD041527 | Pride
H3k9me3 Alzheimer's disease Vgf Proteomics 
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Not available
S-EPMC5224719 | biostudies-literature
UnknownRisk factors for suicidality in Huntington disease: An analysis of the 2CARE clinical trial.
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S-EPMC6448454 | biostudies-literature
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S-EPMC12535838 | biostudies-literature
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S-EPMC12535840 | biostudies-literature
UnknownGWAS and meta-analysis identifies 49 genetic variants underlying critical COVID-19.
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S-EPMC10208981 | biostudies-literature
UnknownA second update on mapping the human genetic architecture of COVID-19.
Not available
S-EPMC10482689 | biostudies-literature
UnknownGenotyping, sequencing and analysis of 140,000 adults from Mexico City.
Not available
S-EPMC10600010 | biostudies-literature
UnknownEfficacy and Safety of Degludec versus Glargine in Type 2 Diabetes.
Not available
S-EPMC5731244 | biostudies-literature
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