Sort   by:  
 Page size 
ProteomicsStimulation of motilin secretion by bile, free fatty acids and acidification in human duodenal organoids
Characterision of the bioactive peptide content of M-cells. M-cells derived from organoids were sorted using FAC sorting techniques and were lysed and analysed by LC-MS/MS using a peptidomics approach.
ORGANISM(S): Homo sapiens (Human) 
2021-11-19 | PXD026621 | Pride
Ghrelin M-cell Organoid Facs Motilin Peptidomics 
ProteomicsPeptidomic analysis of pancreatic neurodendocrine tumours (Glucagonoma)
A peptidomic analysis of plasma from patients with well characterised pancreatic neuroendocrine tumours (PNET) was performed. A nano LC-MS analysis identified a number of peptides from the glucagon gene, which were idenfiried in a previous case study using multiple immunoassays. Peptides to other pr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-31 | MSV000082880 | MassIVE
ProteomicsPeptidomics profiling of murine intestine
The aim of the project is to generate a peptidomics map of gut hormone peptides along the gastrointestinal tract, starting with the stomach and including the duodenum, jejunum, ileum, colon and rectum. The tissues would be collected after surgery and the peptide fraction extracted and anlysed by nan...
ORGANISM(S): Mus musculus (Mouse) 
2019-02-15 | PXD009796 | Pride
Peptidomics Gut hormones Mouse 
ProteomicsPeptidomics profiling of human intestine
The aim of the project is to generate a peptidomics map of gut hormone peptides along the gastrointestinal tract, starting with the stomach and including the duodenum, jejunum, ileum, ascending colon, sigmoid colon and rectum. The tissues would be collected after surgery and the peptide fraction ext...
ORGANISM(S): Homo sapiens (Human) 
2019-02-15 | PXD009788 | Pride
Gut hormone peptides Peptidomics Instestine 
ProteomicsPeptidomics of enteroendocrine cells and characterisation of potential effects of a novel preprogastrin derived-peptide on glucose tolerance in lean mice
To analyse the peptidomics of mouse enteroendocrine cells (EECs) and human gastrointestinal (GI) tissue and identify novel gut derived peptides. High resolution nano-flow liquid chromatography mass spectrometry (LCMS) was performed on (i) flow-cytometry purified NeuroD1 positive cells from mouse an...
ORGANISM(S): Mus musculus (Mouse) 
2021-03-29 | PXD024050 | Pride
Enteroendocrine cells  peptidomics  mass spectrometry  prohormones  granins  progastrin 
Sort   by:  
 Page size