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MetabolomicsBrown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
Brown and beige adipose tissue are emerging as distinct endocrine organs. These tissues are functionally associated with skeletal muscle, adipose tissue metabolism and systemic energy expenditure, suggesting an interorgan signaling network. Using metabolomics, we identify 3-methyl-2-oxovaleric acid,...
2022-03-03 | MTBLS2436 | MetaboLights
TranscriptomicsRNAseq evaluation of nicotinamide seed treatment analysed in Norway spruce seedlings
Nicotinamide seed treatment is investigated as a method for production of robust plants. Previous studies have shown that nicotinamide promotes the plant defence system and decreases DNA methylation levels. The purpose of the present work was to learn more about the underlying molecular mechanisms. ...
ORGANISM(S): Picea abies 
2021-10-15 | E-MTAB-11007 | biostudies-arrayexpress
UnknownSusceptibility to prosocial and antisocial influence in adolescence following mindfulness training.
Not available
S-EPMC10078582 | biostudies-literature
MetabolomicsNitisinone’s mosquitocidal properties hold promise for malaria control

Nitisinone’s mosquitocidal properties hold promise for malaria control

2025-06-16 | MTBLS11617 | MetaboLights
TranscriptomicsRNA-seq of 7G8 cell bank parasites
The parasite Plasmodium falciparum is responsible for severe malaria, which remains a major cause of death, particularly in sub-Saharan Africa. The reference strain NF54 (or its subclone 3D7) is commonly used for controlled human malaria infection (CHMI), but recently strains with a different geogra...
ORGANISM(S): Plasmodium falciparum 7G8 
2022-09-22 | E-MTAB-12157 | biostudies-arrayexpress
MetabolomicsMetabolomics reveals impaired maturation of HDL particles in adolescents with hyperinsulinaemic androgen excess
Hyperinsulinaemic androgen excess (HIAE) in prepubertal and pubertal girls usually precedes a broader pathological phenotype in adulthood that is associated with anovulatory infertility, metabolic syndrome and type 2 diabetes. The metabolic derangements that determine these long-term health risks re...
2015-04-09 | MTBLS103 | MetaboLights
TranscriptomicsTranscriptional regulation of endocrine cell differentiation by Insm1
This experiment used RNA-Seq technology to explore gene expression in mouse Insm1^GFP/Pdx1^CFP HIGH [het/het] FACS sorted pancreatic cells (pre-beta cells) and Insm1^GFP/Pdx1^CFP LOW [het/het] cells (other endocrine progenitors) at E15.5 and E18.5. Comparison of Insm1 +/Pdx HIGH and Insm1 +/Pdx LO...
ORGANISM(S): Mus musculus 
2014-07-01 | E-MTAB-1929 | biostudies-arrayexpress
Genomicsena-DATASET-Hospital Clinic Barcelona-21-07-2015-12:09:53:274-78 - samples
RNASeq sequencing. Each library was sequenced using TruSeq SBS Kit v3-HS, in paired-end mode with a read length of 2 × 76 bp. We generated more than 20 million paired-end reads for each sample in a fraction of a sequencing lane on HiSeq2000 (Illumina Inc.) following the manufacturer’s protoc...
EGAD00001001443 | EGA
TranscriptomicsIdentification of KIL1 targets via RNA-Seq in Zea mays
To understand how the NAC transcription factor KIL1 regulates age-induced senescence and cell death in maize silks, we need to get a genome-wide view on its downstream targets. We propose to compare the transcriptome profiles of GOF and LOF transgenic silk tissue with the profile of wild-type B104 s...
ORGANISM(S): Zea mays 
2022-08-16 | E-MTAB-10850 | biostudies-arrayexpress
TranscriptomicsRNA-seq of the malaria parasite Plasmodium falciparum 3D7 during its intraerythrocytic development cycle
The parasite Plasmodium falciparum is responsible for severe malaria, which is still one of the major causes of death in developing countries. To provide a new RNA-seq reference dataset for its blood-stage transcriptome according to current guidelines and best practices, we performed a time course e...
ORGANISM(S): Plasmodium falciparum 3D7 
2019-07-02 | E-MTAB-7731 | biostudies-arrayexpress
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