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TranscriptomicsThe SaeR/S Gene Regulatory System is Essential for Innate Immune Evasion by Staphylococcus aureus
Methicillin-resistant Staphylococcus aureus (MRSA) is problematic both in hospitals and the community. Currently, we have limited understanding of mechanisms of innate immune evasion used by S. aureus. To that end, we created an isogenic deletion mutant in strain MW2 (USA400) of the saeR/S two-compo...
ORGANISM(S): Staphylococcus aureus 
2010-05-14 | E-GEOD-15067 | biostudies-arrayexpress
TranscriptomicsAn RNAi Screen Identifies TRRAP as a Regulator of Brain Tumor-Initiating Cell Differentiation
Glioblastoma multiforme is the most common and most aggressive type of primary brain tumor. The brain-infiltrative character of glioblastoma makes complete surgical removal of the tumor impossible and neither radiation nor current chemotherapy provide cure. Recent evidence shows that glioblastoma mu...
ORGANISM(S): Homo sapiens 
2011-03-14 | E-GEOD-27931 | biostudies-arrayexpress
GenomicsThe clonal and mutational evolution spectrum of primary triple negative breast cancers
Primary triple negative breast cancers (TNBC) represent approximately 16% of all breast cancers and are a tumour type defined by exclusion,for which comprehensive landscapes of somatic mutation have not been determined. Here we show in 104 early TNBC cases, that at the time of diagnosis these cancer...
EGAS00001000132 | EGA
UnknownGlycemia Reduction in Type 2 Diabetes - Microvascular and Cardiovascular Outcomes.
Not available
S-EPMC9832916 | biostudies-literature
UnknownGlycemia Reduction in Type 2 Diabetes - Glycemic Outcomes.
Not available
S-EPMC9829320 | biostudies-literature
UnknownAssociation of Baseline Characteristics With Insulin Sensitivity and β-Cell Function in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness (GRADE) Study Cohort.
Not available
S-EPMC7818323 | biostudies-literature
UnknownOptimization of Metformin in the GRADE Cohort: Effect on Glycemia and Body Weight.
Not available
S-EPMC7171946 | biostudies-literature
UnknownBaseline Characteristics of Randomized Participants in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE).
Not available
S-EPMC6804613 | biostudies-literature
UnknownAssociation of Glycemia, Lipids, and Blood Pressure With Cognitive Performance in People With Type 2 Diabetes in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE).
Not available
S-EPMC8740937 | biostudies-literature
UnknownHigher burden of cardiometabolic and socioeconomic risk factors in women with type 2 diabetes: an analysis of the Glycemic Reduction Approaches in Diabetes (GRADE) baseline cohort.
Not available
S-EPMC10151943 | biostudies-literature
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