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ProteomicsSWATH-MS Analysis of Gfi1-mutant bone marrow neutrophils
This study investigates the proteomic alterations in bone marrow neutrophils isolated from 5-8 week old Gfi1+/-, Gfi1K403R/-, Gfi1R412X/-, and Gfi1R412X/R412X mice using the SWATH-MS technique. This dataset consists of 26 raw MS files, comprising 13 DDA (for spectral library generation)and 13 DIA (f...
ORGANISM(S): Mus musculus (Mouse) 
2020-04-07 | PXD010943 | Pride
Scn Gfi1 Swath Neutrophil 
GenomicsThe Growth factor independence 1 (GFI1) 36N variant predisposes to Acute Myeloid Leukemia (AML) by inducing epigenetic changes at the Hoxa9 locus
GFI136N is a coding Single Nucleotide Polymorphism (SNP) in the gene GFI1 that increases the risk for Acute myeloid leukemia (AML) by 60%. It is present in 3-5% of Caucasians and has a prevalence of 12% among AML patients. We generated knockin mice expressing either the human GFI136N variant or the ...
ORGANISM(S): Mus musculus 
2012-12-04 | E-GEOD-31657 | biostudies-arrayexpress
GenomicsPCGP MB WGS Full - samples
DATA FILES FOR PCGP MB WGS - Supersedes (EGAD00001000269)
EGAD00001001864 | EGA
GenomicsPCGP MB - samples
OLD DATA FILES FOR SJMB - Superseded by EGAD00001001864
EGAD00001000269 | EGA
GenomicsGenetic landscape of pediatric Medulloblastoma
Medulloblastoma is a heterogenous disease made up of at least four distinct subtypes of disease which appear to exploit and disrupt naturally occurring developmental pathways of cellular growth and hindbrain development. To better understand the driver mutations of this disease, we performed whole g...
EGAS00001000347 | EGA
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