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Endurance exercise improves cardiac performance and affords protection against cardiovascular diseases but the signalling events that mediate these benefits are largely unexplored. Phosphorylation is an widely studied post-translational modification involved in intracellular signalling, and to disco...
ORGANISM(S): Rattus norvegicus (Rat) 
2017-08-24 | PXD006646 | Pride
Receptor tyrosine kinases (RTKs) and protein phosphatases comprise protein families that play crucial roles in cell signaling. However, a comprehensive picture of how RTKs functionally associate with phosphatases remains elusive. We aimed to study this problem by using two protein-protein interactio...
ORGANISM(S): Homo sapiens (Human) 
2017-01-11 | PXD004248 | Pride
Data from ProteomeXchange, PXD ID: PXD002239. Experiment: HILIC_hcd_seaurchin_UN3, file: HILIC_hcd_seaurchin_UN3_F14.mzml. Published as part of Proteomics. 2015 Jul 29 . From the Abstract: {{i}} Fertilization triggers a dynamic symphony of molecular transformations induced by a rapid rise in intrac...
ORGANISM(S): Strongylocentrotus_purpuratus 
Fertilization triggers a dynamic symphony of molecular transformations induced by a rapid rise in intracellular calcium. Most prominent are surface alterations, metabolic activation, cytoskeletal reorganization, and cell cycle reentry. While the activation process appears to be broadly evolutionaril...
ORGANISM(S): Strongylocentrotus purpuratus (Purple sea urchin) 
2015-08-04 | PXD002239 | Pride
Spatially targeted optical microproteomics (STOMP) is a novel proteomics technique for interrogating micron-scale regions of interest (ROI) in mammalian tissue, with no requirement for genetic manipulation. Methanol or formalin fixed specimens are stained with fluorescent dyes or antibodies to visua...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2015-11-18 | PXD002959 | Pride
Antibodies are used in multiple cell biology applications but there are methods to assess antibody quality, riskingdata integrity and repr developed a standard operating procedure using HEK293 cells to score and antibodies for suitability in immunoprecipitation. This method, validated in in fourind...
ORGANISM(S): Homo sapiens (Human) 
2015-07-15 | PXD002534 | Pride
Antibodies are used in multiple cell biology applications but there are methods to assess antibody quality, riskingdata integrity and repr developed a standard operating procedure using HEK293 cells to score and antibodies for suitability in immunoprecipitation. This method, validated in in fourind...
ORGANISM(S): Homo sapiens (Human) 
2015-07-15 | PXD002412 | Pride
Dataset Pertaining to the proteome changes of the cardiac fibroblast in the whole cell, exosome, and soluble secretome.
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2016-08-12 | MSV000080038 | MassIVE
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
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