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Glycolipids and lipids are prominent components of bacterial cell wall that play critical roles not only in maintaining the biofilm formation but also in resistance to environmental stress. PatA is an essential membrane associated acyltransferase involved in the biosynthesis of phosphatidyl-myo-inos...
2023-05-22 | MTBLS6758 | MetaboLights

Cyclic di-GMP (c-di-GMP) is a well-known second messenger that plays a key role in many physiological processes in bacteria. The synthesis of lipids is essential for bacterial biofilm formation. However, whether c-di-GMP signaling modulates the synthesis of lipid and further regulates biofilm for...

2023-12-12 | MTBLS7053 | MetaboLights
Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...
2021-10-06 | MTBLS2343 | MetaboLights
The wild type strain, hpoR knockout strain and overexpression strain of BCG were determined by proteomics
ORGANISM(S): Mycobacterium bovis BCG str. Pasteur 1173P2 
2026-09-07 | PXD039181 | Pride
The wild type strain and patA deletion mutant of Mycobacterium smegmatis were determined proteomically
ORGANISM(S): Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155) 
2023-05-17 | PXD038853 | Pride
The Omicron variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first identified in November 2021 in South Africa, has initiated the 5th wave of global pandemics. Here, we systemically examined immunological and metabolic characteristics of Omicron variants infection. We found ...
ORGANISM(S): Cercopithecus aethiops (Green monkey) (Grivet) 
2023-03-11 | PXD037955 | Pride
In this study, phosphorylation levels of Neospora caninum parasite (Nc1 strains) tachyzoites were compared with PKG inhibitor MBP146-78 treated and untreated, contains two replicates. Therefore, four subprojects are included in this project. Subproject IPX0011618001 is composed of the sub-dataset ge...
ORGANISM(S): Neospora Caninum 
2025-04-09 | PXD062765 |
Deep vein thrombosis (DVT) is a leading cause of morbidity and mortality after trauma. Here, we integrate metabolomics and proteomics in up to 680 individuals with and without DVT after trauma (pt-DVT) to reveal the metabolic alterations and their function, and provide potential biomarkers. We carri...
ORGANISM(S): Homo Sapiens 
2024-07-22 | PXD054131 |
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